Defective T cell development and function in calcineurin A beta -deficient mice (Q28592115)

31 January 2017

title

Defective T cell development and function in calcineurin A beta -deficient mice (English)

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Nuclear factor of activated T-cells, cytoplasmic 1

31 January 2017

main subject

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Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

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Nuclear factor of activated T-cells, cytoplasmic 3

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Protein phosphatase 3, catalytic subunit, beta isoform

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Eric B. Brandt

2

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author name string

Orlando F. Bueno

series ordinal

1

1 reference

31 January 2017

Marc E. Rothenberg

series ordinal

3

1 reference

31 January 2017

Jeffery D. Molkentin

series ordinal

4

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31 January 2017

language of work or name

English

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publication date

9 July 2002

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Proceedings of the National Academy of Sciences of the United States of America

31 January 2017

published in

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31 January 2017

volume

99

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31 January 2017

issue

14

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31 January 2017

page(s)

9398–9403

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Calcineurin: form and function

31 January 2017

cites work

1 reference

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JNK is required for effector T-cell function but not for T-cell activation

17 March 2017

1 reference

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

17 March 2017

1 reference

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NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun

17 March 2017

1 reference

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Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

17 March 2017

2 references

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17 March 2017

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The Syk family of protein tyrosine kinases in T-cell activation and development

22 April 2017

1 reference

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The transcription factor NFAT4 is involved in the generation and survival of T cells

17 March 2017

1 reference

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Transcription factors of the NFAT family: regulation and function

17 March 2017

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

17 March 2017

1 reference

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

17 March 2017

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Manipulating immune responses with immunosuppressive agents that target NFAT.

7 April 2017

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Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

29 September 2017

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Transcriptional regulation of T lymphocyte development and function

29 September 2017

1 reference

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Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

29 September 2017

1 reference

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An enhanced immune response in mice lacking the transcription factor NFAT1.

29 September 2017

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T cell responses in calcineurin A alpha-deficient mice

29 September 2017

1 reference

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Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

29 September 2017

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Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B

29 September 2017

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In vivo and in vitro suppression of T-cell receptor alpha/beta CD4- CD8- T lymphocytes by cyclosporine A.

29 September 2017

1 reference

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Abnormal differentiation of thymocytes in mice treated with cyclosporin A.

3 June 2018

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Murine interleukin-4 displays potent anti-tumor activity in vivo

3 June 2018

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Effects of cyclosporin A on IL-2 production and lymphocyte proliferation during infection of mice with lymphocytic choriomeningitis virus

3 June 2018

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Effects of cyclosporin A and dinactin on T-cell proliferation, interleukin-5 production, and murine pulmonary inflammation.

3 June 2018

1 reference

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Cyclosporine induces cancer progression by a cell-autonomous mechanism.

21 January 2018

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PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

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Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

21 January 2018

1 reference

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Effects of a constitutively active form of calcineurin on T cell activation and thymic selection

27 November 2018

1 reference

12 December 2020

NFATc1 and NFATc2 together control both T and B cell activation and differentiation

1 reference

12 December 2020

Cyclosporin A inhibits positive selection and delays negative selection in alpha beta TCR transgenic mice

1 reference

12 December 2020

Distinct tissue and cellular distribution of two major isoforms of calcineurin

1 reference

12 December 2020

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

12 December 2020

Regulation of allergic inflammation and eosinophil recruitment in mice lacking the transcription factor NFAT1: role of interleukin-4 (IL-4) and IL-5

1 reference

12 December 2020

Calcineurin and the biological effect of cyclosporine and tacrolimus

1 reference

12 December 2020

Transforming growth factor (TGF)-beta mimics and anti-TGF-beta antibody abrogates the in vivo effects of cyclosporine: demonstration of a direct role of TGF-beta in immunosuppression and nephrotoxicity of cyclosporine

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.152665399

1 reference

31 January 2017

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