Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice (Q28593143)

GOA release 2020-03-11

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Nora Stern

1

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31 January 2017

Ayala Hochman

2

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31 January 2017

Naty Zemach

3

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31 January 2017

Nir Weizman

4

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31 January 2017

Ilan Hammel

5

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31 January 2017

Yosef Shiloh

6

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31 January 2017

Galit Rotman

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31 January 2017

Ari Barzilai

Journal of Biological Chemistry

8

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31 January 2017

language of work or name

English

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publication date

4 January 2002

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31 January 2017

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31 January 2017

277

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1

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602–608

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31 January 2017

The genetic defect in ataxia-telangiectasia

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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1 reference

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The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

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ATM: a mediator of multiple responses to genotoxic stress

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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1 reference

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Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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Ataxia telangiectasia mutated is essential during adult neurogenesis

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The many substrates and functions of ATM

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https://api.crossref.org/works/10.1074%2FJBC.M106798200

DNA double-strand breaks: signaling, repair and the cancer connection

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https://api.crossref.org/works/10.1074%2FJBC.M106798200

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

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Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation

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Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

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1 reference

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Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm

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Mitochondrial free radical generation, oxidative stress, and aging

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Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

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A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

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Poly(ADP-ribose) polymerase-1 in the nervous system

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Low catalase activity in xeroderma pigmentosum fibroblasts and SV40-transformed human cell lines is directly related to decreased intracellular levels of the cofactor, NADPH.

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1 reference

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An improved cycling assay for nicotinamide adenine dinucleotide.

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Spectrophotometric determination of oxidized and reduced pyridine nucleotides in erythrocytes using a single extraction procedure

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Cerebral ischemia and reperfusion: prevention of brain mitochondrial injury by lidoflazine.

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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Niacin, poly(ADP-ribose) polymerase-1 and genomic stability

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1 reference

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Linking DNA damage and neurodegeneration

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1 reference

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Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

21 January 2018

1 reference

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Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.

21 January 2018

1 reference

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Extrachromosomal rDNA circles--a cause of aging in yeast

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1 reference

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106798200

New functions of a long-known molecule

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106798200

Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106798200

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

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1 reference

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Kinetics, control, and mechanism of ubiquinone reduction by the mammalian respiratory chain-linked NADH-ubiquinone reductase

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1 reference

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Nuclear retention of ATM at sites of DNA double strand breaks

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1 reference

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Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

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1 reference

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A simple ultramicro method for determination of pyridine nucleotides in tissues

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1 reference

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Thin-layer chromatography of beta-aminopropionitrile

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1 reference

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Oxidative damage in the central nervous system: protection by melatonin

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1 reference

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