Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance (Q28593303)

31 January 2017

title

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance (English)

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Autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)

31 January 2017

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Martin Aichinger

1

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31 January 2017

Chunyan Wu

2

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31 January 2017

Jelena Nedjic

3

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31 January 2017

Ludger Klein

4

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31 January 2017

language of work or name

English

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publication date

11 February 2013

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Journal of Experimental Medicine

31 January 2017

published in

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31 January 2017

volume

210

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31 January 2017

issue

2

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31 January 2017

page(s)

287–300

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Chaperone-mediated autophagy: a unique way to enter the lysosome world

31 January 2017

cites work

1 reference

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Projection of an immunological self shadow within the thymus by the aire protein

17 March 2017

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Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance

29 September 2017

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29 September 2017

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Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export

29 September 2017

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Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells

29 September 2017

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29 September 2017

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Zoned out: functional mapping of stromal signaling microenvironments in the thymus

29 September 2017

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Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes

29 September 2017

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29 September 2017

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A central role for central tolerance

29 September 2017

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Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

29 September 2017

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Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

29 September 2017

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Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens

29 September 2017

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29 September 2017

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Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

29 September 2017

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Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy

29 September 2017

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29 September 2017

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29 September 2017

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CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Antigen compartmentation and T helper cell tolerance induction

3 June 2018

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3 June 2018

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Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

3 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20122149

In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses.

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20122149

Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA.

21 January 2018

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Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.20122149

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20122149

Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20122149

Sampling of complementing self-antigen pools by thymic stromal cells maximizes the scope of central T cell tolerance

21 January 2018

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12 December 2020

Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression

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12 December 2020

CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium

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12 December 2020

Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance

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12 December 2020

NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells

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12 December 2020

Identifiers

DOI

10.1084/JEM.20122149

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1 reference

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