Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation (Q28593921)

GOA release 2020-03-11

author name string

J. Turkson

1

1 reference

31 January 2017

D. Ryan

2

1 reference

31 January 2017

J. S. Kim

3

1 reference

31 January 2017

Y. Zhang

4

1 reference

31 January 2017

Z. Chen

5

1 reference

31 January 2017

E. Haura

6

1 reference

31 January 2017

A. Laudano

7

1 reference

31 January 2017

S. Sebti

8

1 reference

31 January 2017

A. D. Hamilton

9

1 reference

31 January 2017

R. Jove

Journal of Biological Chemistry

10

1 reference

31 January 2017

language of work or name

English

0 references

publication date

30 November 2001

1 reference

31 January 2017

1 reference

31 January 2017

276

1 reference

31 January 2017

45443–45455

1 reference

31 January 2017

48

1 reference

31 January 2017

STATs and gene regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Jaks and Stats in signaling by the cytokine receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

The state of the STATs: recent developments in the study of signal transduction to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

How cells respond to interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Control of myeloid differentiation and survival by Stats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Roles of STAT3 defined by tissue-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

The expression and regulation of STATs during 3T3-L1 adipocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Stat3 activation is required for cellular transformation by v-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

STAT proteins: novel molecular targets for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

STAT signaling in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

The role of STATs in myeloid differentiation and leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

STAT signaling in the pathogenesis and treatment of leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Protein tyrosine kinase inhibitors as novel therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Inhibitors of tyrosine kinases in the treatment of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor [see commetns].

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Functional differences between Stat3alpha and Stat3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Mutational analysis of acute-phase response factor/Stat3 activation and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Prolactin and interleukin-2 receptors in T lymphocytes signal through a MGF-STAT5-like transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Genetic engineering of proteins with cell membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Mutational analysis of the STAT6 SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

The role of STATs in transcriptional control and their impact on cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200

The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107527200