Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation (Q28594146)

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29 January 2020

title

Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351249%20AND%20SRC:MED&resulttype=core&format=json

Mediator complex subunit 1

29 January 2020

main subject

1 reference

GOA release 2020-03-11

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351249%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Susan E. Waltz

5

1 reference

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29 January 2020

3

Mitsuhiro Ito

2 references

31 January 2017

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29 January 2020

author name string

Pingping Jiang

1

2 references

31 January 2017

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29 January 2020

Qiuping Hu

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351249%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Sohaib Khan

6

2 references

31 January 2017

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29 January 2020

Xiaoting Zhang

8

2 references

31 January 2017

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29 January 2020

Robert G Roeder

7

1 reference

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29 January 2020

language of work or name

English

0 references

publication date

29 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351249%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

29 January 2020

published in

2 references

31 January 2017

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29 January 2020

volume

107

2 references

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29 January 2020

issue

15

2 references

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29 January 2020

page(s)

6765-6770

1 reference

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CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes

29 January 2020

cites work

1 reference

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Key stages in mammary gland development: the cues that regulate ductal branching morphogenesis

17 March 2017

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MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription

17 March 2017

1 reference

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Dynamic regulation of pol II transcription by the mammalian Mediator complex

17 March 2017

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Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors

17 March 2017

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Molecular determinants for the tissue specificity of SERMs

17 March 2017

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17 March 2017

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The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro

17 March 2017

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Requirement of helix 1 and the AF-2 domain of the thyroid hormone receptor for coactivation by PGC-1

17 March 2017

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Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

17 March 2017

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The coregulator exchange in transcriptional functions of nuclear receptors

17 March 2017

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Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer

17 March 2017

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17 March 2017

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

17 March 2017

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Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

17 March 2017

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Structure and specificity of nuclear receptor-coactivator interactions

17 March 2017

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The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

17 March 2017

1 reference

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

17 March 2017

1 reference

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Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

17 March 2017

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The nuclear receptor superfamily: the second decade

17 March 2017

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Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

17 March 2017

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

22 April 2017

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Generation of a functional mammary gland from a single stem cell

7 April 2017

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Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene

7 April 2017

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Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family

29 September 2017

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29 September 2017

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Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression

29 September 2017

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Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mediator and the mechanism of transcriptional activation

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Progesterone receptors in mammary gland development and tumorigenesis

29 September 2017

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Molecular portraits and the family tree of cancer

29 September 2017

1 reference

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Signaling pathways in mammary gland development.

29 September 2017

1 reference

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Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872411

Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872411

Lasker Basic Medical Research Award. The eukaryotic transcriptional machinery: complexities and mechanisms unforeseen.

29 September 2017

1 reference

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Molecular signatures predict outcomes of breast cancer

3 June 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20351249

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1001814107

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351249%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351249%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

2 references

31 January 2017