The mediator of RNA polymerase II. (Q36029267)

11 August 2017

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title

The mediator of RNA polymerase II. (English)

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11 August 2017

Erik Blazek

1

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PubMed ID

15690163

11 August 2017

Gerhard Mittler

series ordinal

2

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PubMed ID

15690163

11 August 2017

Michael Meisterernst

series ordinal

3

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11 August 2017

3 February 2005

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11 August 2017

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11 August 2017

113

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11 August 2017

8

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11 August 2017

399-408

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https://scigraph.springernature.com/pub.10.1007/s00412-005-0329-5

11 August 2017

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cites work

RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00412-005-0329-5

GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00412-005-0329-5

Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme

21 January 2018

1 reference

12 December 2020

The NC2 repressor is dispensable in yeast mutated for the Sin4p component of the holoenzyme and plays roles similar to Mot1p in vivo

1 reference

12 December 2020

Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex

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12 December 2020

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

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12 December 2020

Assembly of a Mediator/TFIID/TFIIA Complex Bypasses the Need for an Activator

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12 December 2020

An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p

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12 December 2020

The structural and functional organization of the yeast mediator complex

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12 December 2020

Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit

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12 December 2020

Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae

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12 December 2020

NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription

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12 December 2020

In vivo association of adenovirus large E1A protein with the human mediator complex in adenovirus-infected and -transformed cells.

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12 December 2020

Five SWI genes are required for expression of the HO gene in yeast

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12 December 2020

Structural organization of yeast and mammalian mediator complexes

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12 December 2020

Regulatory diversity among metazoan co-activator complexes

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12 December 2020

Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53

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12 December 2020

Transcription. Mediator meets morpheus

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12 December 2020

Coactivators for the orphan nuclear receptor RORalpha

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12 December 2020

Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II

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12 December 2020

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

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12 December 2020

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

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12 December 2020

A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast

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12 December 2020

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

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12 December 2020

Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

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12 December 2020

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains

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12 December 2020

A single point mutation in TFIIA suppresses NC2 requirement in vivo

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12 December 2020

Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer

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12 December 2020

Ty-mediated gene expression of the LYS2 and HIS4 genes of Saccharomyces cerevisiae is controlled by the same SPT genes

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12 December 2020

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

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12 December 2020

Mediator of Transcriptional Regulation

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12 December 2020

MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators

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12 December 2020

Conserved structures of mediator and RNA polymerase II holoenzyme

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12 December 2020

Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module

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12 December 2020

Dissecting the regulatory circuitry of a eukaryotic genome

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12 December 2020

Targeting of Swi/Snf to the yeast GAL1 UAS G requires the Mediator, TAF IIs, and RNA polymerase II.

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12 December 2020

Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation

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12 December 2020

Recruitment of SWI/SNF by Gcn4p Does Not Require Snf2p or Gcn5p but Depends Strongly on SWI/SNF Integrity, SRB Mediator, and SAGA

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12 December 2020

Mediator complexes and transcription.

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12 December 2020

Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification

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12 December 2020

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

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12 December 2020

Ligand-inducible interaction of the DRIP/TRAP coactivator complex with retinoid receptors in retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells

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12 December 2020

Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

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12 December 2020

Drosophila Med6 is required for elevated expression of a large but distinct set of developmentally regulated genes

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12 December 2020

Distinct conformational states of nuclear receptor-bound CRSP-Med complexes

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12 December 2020

Structure, function, and activator-induced conformations of the CRSP coactivator

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12 December 2020

Yeast nuclear extract contains two major forms of RNA polymerase II mediator complexes

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12 December 2020

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

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12 December 2020

Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro

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12 December 2020

Role of metazoan mediator proteins in interferon-responsive transcription

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12 December 2020

Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells

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12 December 2020

The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs

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12 December 2020

Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF

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12 December 2020

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

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12 December 2020

The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator

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12 December 2020

A protein interaction map of Drosophila melanogaster

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12 December 2020

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

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12 December 2020

hSrb7, an essential human Mediator component, acts as a coactivator for the thyroid hormone receptor

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12 December 2020

Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo

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12 December 2020

Selective coactivator interactions in gene activation by SREBP-1a and -1c.

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12 December 2020

Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae

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12 December 2020

Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

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12 December 2020

TFIIH is negatively regulated by cdk8-containing mediator complexes

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12 December 2020

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

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12 December 2020

A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex

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12 December 2020

Dynamics of enhancer-promoter communication during differentiation-induced gene activation.

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12 December 2020

Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae

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12 December 2020

LALNVIEW: a graphical viewer for pairwise sequence alignments.

1 reference

12 December 2020

Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors

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12 December 2020

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

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12 December 2020

A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction.

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12 December 2020

Transcriptional coactivator complexes

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12 December 2020

A high resolution protein interaction map of the yeast Mediator complex

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12 December 2020

Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB.

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12 December 2020

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

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12 December 2020

Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor

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12 December 2020

External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator

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12 December 2020

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

1 reference

12 December 2020

Identification of DRIP205 as a coactivator for the Farnesoid X receptor.

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12 December 2020

Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ERalpha and ERbeta

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12 December 2020

TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.

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12 December 2020

Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man

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12 December 2020

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

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12 December 2020

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro

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12 December 2020

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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12 December 2020

Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3

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12 December 2020

Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro.

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12 December 2020

A mediator required for activation of RNA polymerase II transcription in vitro

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12 December 2020

Cofactor requirements for transcriptional activation by Sp1.

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12 December 2020

Mechanism of transcriptional activation by Sp1: evidence for coactivators

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12 December 2020

Mutants of yeast defective in sucrose utilization.

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12 December 2020

RNA polymerase II (Pol II)-TFIIF and Pol II-mediator complexes: the major stable Pol II complexes and their activity in transcription initiation and reinitiation

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12 December 2020

A transcription reinitiation intermediate that is stabilized by activator

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12 December 2020

intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation.

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12 December 2020

Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae

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12 December 2020

The general transcription factors of RNA polymerase II

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12 December 2020

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.

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12 December 2020

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology

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12 December 2020

Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s

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12 December 2020

Independent recruitment in vivo by Gal4 of two complexes required for transcription

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12 December 2020

Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates

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12 December 2020

Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters

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12 December 2020

Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction

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12 December 2020

RB18A, whose gene is localized on chromosome 17q12-q21.1, regulates in vivo p53 transactivating activity

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12 December 2020

Role of mediator in transcriptional activation by the aryl hydrocarbon receptor

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12 December 2020

A recombinant RNA polymerase II-like enzyme capable of promoter-specific transcription

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12 December 2020

TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA

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12 December 2020

Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells

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12 December 2020

A component of the ARC/Mediator complex required for TGF beta/Nodal signalling

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12 December 2020

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II

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12 December 2020

BRCA1 function mediates a TRAP/DRIP complex through direct interaction with TRAP220

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12 December 2020

The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development

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12 December 2020

SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex

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12 December 2020

Ras induces mediator complex exchange on C/EBP beta

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12 December 2020

Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

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12 December 2020

The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

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12 December 2020

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors

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12 December 2020

Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter

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12 December 2020

10.1007/S00412-005-0329-5

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15690163