Mechanism of GTP hydrolysis by G-protein alpha subunits (Q28646200)

2

1 reference

3 February 2017

E. Lee

3

1 reference

3 February 2017

S. R. Sprang

4

1 reference

3 February 2017

A. G. Gilman

Proceedings of the National Academy of Sciences of the United States of America

5

1 reference

3 February 2017

language of work or name

English

0 references

publication date

11 October 1994

1 reference

3 February 2017

1 reference

3 February 2017

91

1 reference

3 February 2017

21

1 reference

3 February 2017

9828–9831

1 reference

3 February 2017

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Rapid and efficient site-specific mutagenesis without phenotypic selection

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Crystal structure of an active form of RAS protein, a complex of a GTP analog and the HRAS p21 catalytic domain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Two G protein oncogenes in human endocrine tumors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

The GTPase superfamily: conserved structure and molecular mechanism

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

G proteins: transducers of receptor-generated signals

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Diversity of G proteins in signal transduction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Crystal structure of active elongation factor Tu reveals major domain rearrangements

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Mutations of GS alpha designed to alter the reactivity of the protein with bacterial toxins. Substitutions at ARG187 result in loss of GTPase activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Expression of Gs alpha in Escherichia coli. Purification and properties of two forms of the protein.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Structure and function of signal-transducing GTP-binding proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

19F and 31P NMR spectroscopy of G protein alpha subunits. Mechanism of activation by Al3+ and F-.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Asparagine 26, glutamic acid 31, valine 45, and tyrosine 64 of Ras proteins are required for their oncogenicity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Expression of G-protein alpha subunits in Escherichia coli.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44910

Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7937899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crystallization and Preliminary Crystallographic Studies of Giα1 and Mutants of Giα1 in the GTP and GDP-bound States

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7937899

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluoroaluminates activate transducin-GDP by mimicking the gamma-phosphate of GTP in its binding site

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7937899