The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency (Q28678671)

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scientific article published on April 1, 1991

Language	Label	Description	Also known as
English	The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency	scientific article published on April 1, 1991

Statements

scholarly article

1 reference

6 February 2017

The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency (English)

1 reference

6 February 2017

phosphorylation

0 references

signal transduction

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1672440

25 October 2022

1 reference

10.1128/MCB.11.4.2040-2048.1991

https://api.crossref.org/works/10.1128/MCB.11.4.2040-2048.1991

25 October 2022

author name string

F. Fazioli

1

1 reference

6 February 2017

U. H. Kim

2

1 reference

6 February 2017

S. G. Rhee

3

1 reference

6 February 2017

C. J. Molloy

4

1 reference

6 February 2017

O. Segatto

5

1 reference

6 February 2017

P. P. Di Fiore

6

1 reference

6 February 2017

language of work or name

0 references

publication date

1 April 1991

1 reference

6 February 2017

full work available at URL

http://mcb.asm.org/cgi/content/abstract/11/4/2040

online access status

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1672440

25 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1672440/pdf/?tool=EBI

Portable Document Format

online access status

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1672440

25 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1672440/?tool=EBI

online access status

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1672440

25 October 2022

https://europepmc.org/articles/PMC359891

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1672440

25 October 2022

https://europepmc.org/articles/PMC359891?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1672440

25 October 2022

https://journals.asm.org/doi/pdf/10.1128/mcb.11.4.2040-2048.1991

1 reference

10.1128/MCB.11.4.2040-2048.1991

https://api.crossref.org/works/10.1128/MCB.11.4.2040-2048.1991

25 October 2022

Molecular and Cellular Biology

1 reference

6 February 2017

11

1 reference

6 February 2017

4

1 reference

6 February 2017

2040–2048

1 reference

6 February 2017

A new technique for the assay of infectivity of human adenovirus 5 DNA

1 reference

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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

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Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

1 reference

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17 March 2017

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1 reference

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

1 reference

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17 March 2017

Stimulation of phospholipase C-gamma 1 membrane association by epidermal growth factor

1 reference

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17 March 2017

Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptor

1 reference

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17 March 2017

Identification of two epidermal growth factor-sensitive tyrosine phosphorylation sites of phospholipase C-gamma in intact HSC-1 cells

1 reference

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17 March 2017

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1 reference

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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

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Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

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Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase

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The neu oncogene encodes an epidermal growth factor receptor-related protein

1 reference

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3 June 2018

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

1 reference

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Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity

1 reference

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Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene

1 reference

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3 June 2018

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

1 reference

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3 June 2018

S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C

1 reference

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3 June 2018

HER2 cytoplasmic domain generates normal mitogenic and transforming signals in a chimeric receptor

1 reference

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3 June 2018

A chimeric EGF-R-neu proto-oncogene allows EGF to regulate neu tyrosine kinase and cell transformation

1 reference

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3 June 2018

The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

1 reference

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3 June 2018

Phospholipase C-gamma, a substrate for PDGF receptor kinase, is not phosphorylated on tyrosine during the mitogenic response to CSF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359891

3 June 2018

Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C

1 reference

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Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells

1 reference

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NIH3T3 fibroblasts transformed by the dbl oncogene show altered expression of bradykinin receptors: effect on inositol lipid turnover.

1 reference

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PDGF induction of tyrosine phosphorylation of GTPase activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359891

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Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

1 reference

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Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo

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Inhibition of serum- and ras-stimulated DNA synthesis by antibodies to phospholipase C.

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1 reference

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EGF receptor and erbB-2 tyrosine kinase domains confer cell specificity for mitogenic signaling

1 reference

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1 reference

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Activation of phosphatidylinositol 3-kinase by insulin

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The normal erbB-2 product is an atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand.

1 reference

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The role of autophosphorylation in modulation of erbB-2 transforming function

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Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex

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Monoclonal antibodies to three phospholipase C isozymes from bovine brain

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based on heuristic

inferred from PubMed ID database lookup

EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/1672440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1672440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.11.4.2040

0 references

10.1128/MCB.11.4.2040-2048.1991

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1672440

25 October 2022

0 references

1 reference

6 February 2017

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