IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients (Q28710292)

23

Capucine Picard

0 references

Sandra Weller

Sandra Weller

1

0 references

Maya Chrabieh

Maya Chrabieh

5

0 references

Alexandre Alcais

Alexandre Alcais

20

0 references

Shen-Ying Zhang

Shen-Ying Zhang

19

0 references

Carlos Rodrigo

Carlos Rodrigo

15

0 references

Andrea Cerutti

Andrea Cerutti

17

0 references

Jean-Laurent Casanova

Jean-Laurent Casanova

22

0 references

Claude-Agnès Reynaud

25

Claude-Agnès Reynaud

0 references

Ben-Zion Garty

8

Ben-Zion Garty

0 references

Yildiz Camcioglu

13

Yildiz Camcioglu

0 references

Eric Meffre

18

Eric Meffre

0 references

Andrew C Issekutz

10

Andrew C Issekutz

0 references

Chaim M Roifman

9

Chaim Roifman

0 references

László Maródi

6

László Maródi

0 references

Carlos Rodríguez-Gallego

7

Carlos Rodriguez-Gallego

0 references

Cyrille Hoarau

12

Cyrille Hoarau

0 references

Simona Eva Zitnik

11

Simona Eva Zitnik

0 references

author name string

Mélanie Bonnet

2

0 references

Héloïse Delagreverie

3

0 references

Laura Israel

4

0 references

Júlia Vasconcelos

14

0 references

Peter D Arkwright

16

0 references

Jean-Claude Weill

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

24

0 references

language of work or name

English

0 references

publication date

13 December 2012

0 references

published in

Blood

0 references

volume

120

0 references

issue

25

0 references

page(s)

4992-5001

0 references

cites work

1 reference

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B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

17 March 2017

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Oncogenically active MYD88 mutations in human lymphoma

17 March 2017

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The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

17 March 2017

1 reference

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IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans

17 March 2017

1 reference

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Pyogenic bacterial infections in humans with MyD88 deficiency

17 March 2017

1 reference

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

17 March 2017

1 reference

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Herpes simplex virus encephalitis in human UNC-93B deficiency

17 March 2017

1 reference

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

17 March 2017

1 reference

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Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88

17 March 2017

1 reference

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Toll-like receptor signalling

17 March 2017

1 reference

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Pyogenic bacterial infections in humans with IRAK-4 deficiency

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

17 March 2017

1 reference

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TIRAP: an adapter molecule in the Toll signaling pathway

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Integration of B cell responses through Toll-like receptors and antigen receptors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Molecular modeling-based evaluation of hTLR10 and identification of potential ligands in Toll-like receptor signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Toll-like receptors--sentries in the B-cell response

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

The follicular versus marginal zone B lymphocyte cell fate decision

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human marginal zone B cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

IL-1, IL-18, and IL-33 families of cytokines

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+ IgD+ CD27+ B cell repertoire in infants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

TLR3 deficiency in patients with herpes simplex encephalitis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human IgM+CD27+ B cells: memory B cells or "memory" B cells?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiency.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

TLR ligation triggers somatic hypermutation in transitional B cells inducing the generation of IgM memory B cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Reference values for B cell subpopulations from infancy to adulthood.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

CpG drives human transitional B cells to terminal differentiation and production of natural antibodies

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

A distinct Toll-like receptor repertoire in human tonsillar B cells, directly activated by PamCSK, R-837 and CpG-2006 stimulation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525023

Human memory B lymphocyte subsets fulfill distinct roles in the anti-polysaccharide and anti-protein immune response

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23002119

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23002119

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2012-07-440776

1 reference

3083300

3083300

1 reference

1 reference

1 reference