Role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity (Q28710568)

4

object named as

Hans-Georg Kräusslich

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Alex de Marco

object named as

Alex de Marco

1

0 references

Bärbel Glass

3

object named as

Bärbel Glass

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author name string

Anke-Mareil Heuser

2

0 references

Barbara Müller

5

0 references

John A G Briggs

HIV-1 protease and reverse transcriptase control the architecture of their nucleocapsid partner

6

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language of work or name

English

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publication date

December 2012

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published in

Journal of Virology

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volume

86

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issue

24

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page(s)

13708-16

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cites work

1 reference

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The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

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Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates

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Computer visualization of three-dimensional image data using IMOD

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Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

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HIV-1 assembly, budding, and maturation

7 April 2017

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Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity

3 June 2018

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Assembly and architecture of HIV.

3 June 2018

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Role of Gag in HIV Resistance to Protease Inhibitors

3 June 2018

1 reference

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Flexible nature and specific functions of the HIV-1 nucleocapsid protein

3 June 2018

1 reference

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The role of cellular factors in promoting HIV budding

3 June 2018

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The molecular architecture of HIV.

3 June 2018

1 reference

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On the role of the SP1 domain in HIV-1 particle assembly: a molecular switch?

3 June 2018

1 reference

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The relationship between HIV-1 genome RNA dimerization, virion maturation and infectivity

3 June 2018

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Structural analysis of HIV-1 maturation using cryo-electron tomography

3 June 2018

1 reference

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HIV-1 maturation inhibitor bevirimat stabilizes the immature Gag lattice

3 June 2018

1 reference

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Features, processing states, and heterologous protein interactions in the modulation of the retroviral nucleocapsid protein function

3 June 2018

1 reference

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Nucleic acid chaperone activity of retroviral Gag proteins

3 June 2018

1 reference

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Conserved and variable features of Gag structure and arrangement in immature retrovirus particles

3 June 2018

1 reference

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Fundamental differences between the nucleic acid chaperone activities of HIV-1 nucleocapsid protein and Gag or Gag-derived proteins: biological implications

3 June 2018

1 reference

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Human immunodeficiency virus type 1 nucleocapsid p1 confers ESCRT pathway dependence

3 June 2018

1 reference

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HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity.

3 June 2018

1 reference

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Structure and assembly of immature HIV

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Uncoupling human immunodeficiency virus type 1 Gag and Pol reading frames: role of the transframe protein p6* in viral replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Mutational analysis of the C-terminal gag cleavage sites in human immunodeficiency virus type 1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Nucleic acid chaperone activity of HIV-1 nucleocapsid protein: critical role in reverse transcription and molecular mechanism

3 June 2018

1 reference

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The stoichiometry of Gag protein in HIV-1.

3 June 2018

1 reference

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Mutation of the major 5' splice site renders a CMV-driven HIV-1 proviral clone Tat-dependent: connections between transcription and splicing.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Structural organization of authentic, mature HIV-1 virions and cores

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Image reconstructions of helical assemblies of the HIV-1 CA protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Highly purified human immunodeficiency virus type 1 reveals a virtual absence of Vif in virions.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

A putative alpha-helical structure which overlaps the capsid-p2 boundary in the human immunodeficiency virus type 1 Gag precursor is crucial for viral particle assembly

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Cryo-electron microscopy reveals ordered domains in the immature HIV-1 particle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Role of capsid sequence and immature nucleocapsid proteins p9 and p15 in Human Immunodeficiency Virus type 1 genomic RNA dimerization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Rapid kinetics of protein-nucleic acid interaction is a major component of HIV-1 nucleocapsid protein's nucleic acid chaperone function

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Assembly and analysis of conical models for the HIV-1 core.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: an electron microscopy investigation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Ordered aggregation of ribonucleic acids by the human immunodeficiency virus type 1 nucleocapsid protein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503038

Transmission electron microscopy reveals an optimal HIV-1 nucleocapsid aggregation with single-stranded nucleic acids and the mature HIV-1 nucleocapsid protein

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23055560

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23055560