Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models (Q28729944)

2

0 references

Manping Wang

3

0 references

Camellia Adams

4

0 references

Theresa Shek

5

0 references

Kathy Hötzel

6

0 references

Brad Bolon

7

0 references

Ronald Ferrando

8

0 references

Craig Blackmore

9

0 references

Kurt Schroeder

10

0 references

Luis A Rodriguez

11

0 references

Maria Hristopoulos

12

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Rayna Venook

13

0 references

Avi Ashkenazi

14

0 references

Luc R Desnoyers

Creative Commons Attribution 4.0 International

15

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language of work or name

English

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publication date

2012

0 references

published in

PLOS One

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volume

7

0 references

issue

5

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page(s)

e36713

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copyright license

start time

15 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization

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Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

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Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma

17 March 2017

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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

17 March 2017

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17 March 2017

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FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome

17 March 2017

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Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

17 March 2017

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Amplification of fgfr4 gene in human breast and gynecological cancers

17 March 2017

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Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics.

17 March 2017

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Resistance to chemotherapy is associated with fibroblast growth factor receptor 4 up-regulation

3 June 2018

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Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis

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Structural basis for fibroblast growth factor receptor activation

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Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer

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Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

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Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells

3 June 2018

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Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.

3 June 2018

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Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

21 January 2018

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Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.

21 January 2018

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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

21 January 2018

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Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele

21 January 2018

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Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22615798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0036713

1 reference

release_xxi4b6ccq5gbviysq6dqk4d7ee

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xxi4b6ccq5gbviysq6dqk4d7ee

mapped directly with Wikidata item

24 November 2022

based on heuristic

1676329

1 reference

1 reference

1 reference