Thyroid hormone receptors mutated in liver cancer function as distorted antimorphs (Q28752413)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434963%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Thyroid hormone receptors mutated in liver cancer function as distorted antimorphs (English)

1 reference

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16 January 2020

1 reference

1

1 reference

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16 January 2020

author name string

M L Privalsky

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434963%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

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publication date

23 January 2006

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16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434963%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

25

1 reference

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16 January 2020

issue

25

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16 January 2020

page(s)

3576-3588

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Thyroid hormone receptors/THR genes in human cancer

16 January 2020

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16 March 2017

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Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors

16 March 2017

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The nuclear receptor superfamily: the second decade

16 March 2017

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Structural determinants of nuclear receptor assembly on DNA direct repeats

16 March 2017

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The c-erb-A gene encodes a thyroid hormone receptor

16 March 2017

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16 March 2017

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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

16 March 2017

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16 March 2017

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Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties

9 May 2017

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Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors

3 June 2018

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An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis

3 June 2018

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SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways

3 June 2018

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Retinoic acid receptor-alpha is stabilized in a repressive state by its C-terminal, isotype-specific F domain.

3 June 2018

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The thyroid hormone receptor is a suppressor of ras-mediated transcription, proliferation, and transformation

3 June 2018

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Gene repression by nuclear hormone receptors

3 June 2018

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An update on the molecular genetics of hepatocellular carcinoma.

3 June 2018

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The role of corepressors in transcriptional regulation by nuclear hormone receptors

3 June 2018

1 reference

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Germline and somatic thyroid hormone receptor mutations in man.

3 June 2018

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Role of coactivators and corepressors in the induction of the RARbeta gene in human colon cancer cells

3 June 2018

1 reference

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Thyroid hormone receptor alpha 1 (c-erb A alpha 1) suppressed transforming phenotype of nasopharyngeal carcinoma cell line

3 June 2018

1 reference

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Review: molecular thyroidology.

3 June 2018

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Corepressors and nuclear hormone receptor function.

3 June 2018

1 reference

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Impaired interaction of mutant thyroid hormone receptors associated with human hepatocellular carcinoma with transcriptional coregulators

3 June 2018

1 reference

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Steroid hormone receptors: an update

3 June 2018

1 reference

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The mechanism of action of thyroid hormones

3 June 2018

1 reference

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Resistance to thyroid hormone (RTH) syndrome reveals novel determinants regulating interaction of T3 receptor with corepressor

3 June 2018

1 reference

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Molecular basis of resistance to thyroid hormone (RTH).

3 June 2018

1 reference

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Transcriptional silencing is defined by isoform- and heterodimer-specific interactions between nuclear hormone receptors and corepressors

3 June 2018

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Requirement of corepressor binding of thyroid hormone receptor mutants for dominant negative inhibition

3 June 2018

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Nuclear receptors: structure, function and involvement in disease

3 June 2018

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A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release

3 June 2018

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Lack of loss of heterozygosity at the c-erbA beta locus in gastrointestinal tumors

3 June 2018

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Nuclear receptor coactivators and corepressors

3 June 2018

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Thyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors

3 June 2018

1 reference

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Some new twists in the regulation of gene expression by thyroid hormone and retinoic acid receptors

3 June 2018

1 reference

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Different DNA elements can modulate the conformation of thyroid hormone receptor heterodimer and its transcriptional activity

3 June 2018

1 reference

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Intracellular receptors use a common mechanism to interpret signaling information at response elements

3 June 2018

1 reference

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DNA recognition by normal and oncogenic thyroid hormone receptors. Unexpected diversity in half-site specificity controlled by non-zinc-finger determinants

3 June 2018

1 reference

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Syndrome of resistance to thyroid hormone: insights into thyroid hormone action

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701908

Thyroid hormone receptors: multiple forms, multiple possibilities

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701908

Nuclear receptor/AP-1 interaction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701908

Nuclear hormone receptors involved in neoplasia: erb A exhibits a novel DNA sequence specificity determined by amino acids outside of the zinc-finger domain

3 June 2018

1 reference

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v-erbA acts on retinoic acid receptors in immature avian erythroid cells

3 June 2018

1 reference

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Thyroid abnormalities and hepatocellular carcinoma in mice transgenic for v-erbA.

3 June 2018

1 reference

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A structural role for hormone in the thyroid hormone receptor.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701908

Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701908

V-erbA and c-erbA proteins enhance transcriptional activation by c-jun.

3 June 2018

1 reference

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A tumor suppressor role for thyroid hormone beta receptor in a mouse model of thyroid carcinogenesis

3 June 2018

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Thyroid hormone receptor mutations in cancer.

27 November 2018

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Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone

27 November 2018

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Expression of mutant thyroid hormone nuclear receptors is associated with human renal clear cell carcinoma

27 November 2018

1 reference

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Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor

27 November 2018

1 reference

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Very strong correlation between dominant negative activities of mutant thyroid hormone receptors and their binding avidity for corepressor SMRT.

27 November 2018

1 reference

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Molecular and structural biology of thyroid hormone receptors.

27 November 2018

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Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.

27 November 2018

1 reference

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Mechanisms of thyroid hormone action: insights from X-ray crystallographic and functional studies.

27 November 2018

1 reference

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Lack of Coactivator Interaction Can Be a Mechanism for Dominant Negative Activity by Mutant Thyroid Hormone Receptors1

27 November 2018

1 reference

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A novel mechanism of action for v-ErbA: abrogation of the inactivation of transcription factor AP-1 by retinoic acid and thyroid hormone receptors.

27 November 2018

1 reference

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Multiple isoforms of thyroid hormone receptor: an analysis of their relative contribution in mediating thyroid hormone action

27 November 2018

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12 December 2020

Expression of mutant thyroid hormone nuclear receptors in human hepatocellular carcinoma cells

1 reference

12 December 2020

The thyroid hormone receptor interferes with transcriptional activation via the AP-1 complex

1 reference

12 December 2020

Resistance to thyroid hormone

1 reference

12 December 2020

Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor

1 reference

12 December 2020

Loss of heterozygosity of the thyroid hormone receptor B in posterior uveal melanoma

1 reference

12 December 2020

Resistance to thyroid hormone

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12 December 2020

Stoichiometric and steric principles governing repression by nuclear hormone receptors

1 reference

12 December 2020

Dominant negative activity of mutant thyroid hormone alpha1 receptors from patients with hepatocellular carcinoma

1 reference

12 December 2020

Nuclear corepressors enhance the dominant negative activity of mutant receptors that cause resistance to thyroid hormone

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12 December 2020

Thyroid hormone receptor coactivators and corepressors

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12 December 2020

Alterations of thyroid hormone receptor alpha gene: frequency and association with Nm23 protein expression and metastasis in gastric cancer

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12 December 2020

Functionally impaired TR mutants are present in thyroid papillary cancer

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12 December 2020

Resistance to thyroid hormone

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209389

7 January 2021

inferred from DOI database lookup

Liver pathology in obesity

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209389

7 January 2021

inferred from DOI database lookup

Clients' Experiences of Obstructive Silence: Integrating Conscious Reports and Analytic Theories

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209389

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.ONC.1209389

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434963%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16434963%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

16434963

1 reference