A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3) (Q28943455)

14 March 2017

title

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3) (English)

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genome-wide association study

14 March 2017

main subject

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41

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Andreas Engert

21

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Bengt Glimelius

28

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Victor Enciso-Mora

1

Victor Enciso-Mora

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Robert Hofstra

37

Robert Hofstra

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Elke Pogge von Strandmann

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22

Elke Pogge von Strandmann

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26

Hans-Olov Adami

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5

Henrik Hjalgrim

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25

Karin E. Smedby

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43

Mads Melbye

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Stephen Hamilton-Dutoit

29

Stephen Hamilton-Dutoit

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Peter Broderick

Peter Broderick

2

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Tom Van Wezel

Tom van Wezel

39

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Klaus Rostgaard

Klaus Rostgaard

42

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Anke van den Berg

Anke van den Berg

7

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Asta Försti

13

Asta Försti

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6

Kari Hemminki

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15

Annegien Broeks

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34

Ellen T. Chang

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44

Anthony J. Swerdlow

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4

Ruth F. Jarrett

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45

Richard S. Houlston

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31

Lars P. Ryder

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20

Eve Roman

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17

Lesley Shield

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18

Annette Lake

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24

Ilja M. Nolte

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11

Tracy Lightfoot

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12

Flora E. van Leeuwen

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Yussanne Ma

3

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Bianca Olver

8

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Amy Lloyd

9

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Sara E. Dobbins

10

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Arjan Diepstra

14

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Jayaram Vijayakrishnan

16

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Dorothy Montgomery

19

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Katrin S. Reiners

23

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Nicola S. Russell

27

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Marieke de Bruin

30

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Daniel Molin

32

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Karina Meden Sorensen

33

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Malcolm Taylor

35

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Rosie Cooke

36

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Helga Westers

38

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Ronald van Eijk

40

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14 March 2017

language of work or name

English

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publication date

1 December 2010

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14 March 2017

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volume

42

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issue

12

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14 March 2017

page(s)

1126–1130

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describes a project that uses

14 March 2017

genome-wide association study

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The Haematological Malignancy Research Network (HMRN): a new information strategy for population based epidemiology and health service research

inferred from title

cites work

1 reference

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Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia

16 March 2017

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GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation

16 March 2017

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HLA-A*02 is associated with a reduced risk and HLA-A*01 with an increased risk of developing EBV+ Hodgkin lymphoma

16 March 2017

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16 March 2017

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16 March 2017

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Principal components analysis corrects for stratification in genome-wide association studies

16 March 2017

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16 March 2017

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16 March 2017

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Expression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomas

16 March 2017

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16 March 2017

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The structure of haplotype blocks in the human genome

16 March 2017

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Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

16 March 2017

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Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas

16 March 2017

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Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

16 March 2017

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Relative impact of nucleotide and copy number variation on gene expression phenotypes

7 April 2017

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7 April 2017

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A fine-scale map of recombination rates and hotspots across the human genome

7 April 2017

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HLA-A alleles and infectious mononucleosis suggest a critical role for cytotoxic T-cell response in EBV-related Hodgkin lymphoma

7 April 2017

1 reference

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Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

3 June 2018

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The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

3 June 2018

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Regulatory T cells and EBV associated malignancies

3 June 2018

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Mutations of NFKBIA, encoding IkappaB alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases

3 June 2018

1 reference

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TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

3 June 2018

1 reference

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c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells

3 June 2018

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The biology of Hodgkin's lymphoma

3 June 2018

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Infectious aetiology of Hodgkin and non-Hodgkin lymphomas: a review of the epidemiological evidence

3 June 2018

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Sequence variant on 8q24 confers susceptibility to urinary bladder cancer

3 June 2018

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Pvt1-encoded microRNAs in oncogenesis

3 June 2018

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3 June 2018

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3 June 2018

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c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3.

3 June 2018

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A common variant associated with prostate cancer in European and African populations

3 June 2018

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3 June 2018

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3 June 2018

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The Scotland and Newcastle epidemiological study of Hodgkin's disease: impact of histopathological review and EBV status on incidence estimates.

3 June 2018

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Epidemiology of Hodgkin's disease and non-Hodgkin's lymphoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Increased risk of breast cancer following irradiation for Hodgkin's disease is not a result of ATM germline mutations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Localization of predisposition to Hodgkin disease in the HLA class II region.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Assessing the role of HLA-linked and unlinked determinants of disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Pvt-1 transcripts are found in normal tissues and are altered by reciprocal(6;15) translocations in mouse plasmacytomas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Amplification of the c-myc and the pvt-like region in human multiple myeloma

3 June 2018

1 reference

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Breast cancer risk in female survivors of Hodgkin's lymphoma: lower risk after smaller radiation volumes.

3 June 2018

1 reference

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The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

26 November 2018

1 reference

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A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

26 November 2018

1 reference

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Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Whole genome amplification on DNA from filter paper blood spot samples: an evaluation of selected systems.

26 November 2018

1 reference

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Infectious Mononucleosis, Childhood Social Environment, and Risk of Hodgkin Lymphoma

26 November 2018

1 reference

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PReMod: a database of genome-wide mammalian cis-regulatory module predictions

26 November 2018

1 reference

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Does smoking or alcohol modify the risk of Epstein-Barr virus-positive or -negative Hodgkin lymphoma?

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

A genome screen of families at high risk for Hodgkin lymphoma: evidence for a susceptibility gene on chromosome 4.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Ultraviolet Radiation Exposure and Risk of Malignant Lymphomas

26 November 2018

1 reference

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Identification of a commonly amplified 4.3 Mb region with overexpression of C8FW, but not MYC in MYC-containing double minutes in myeloid malignancies

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Familial aggregation of Hodgkin lymphoma and related tumors

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

An epidemiologic study of index and family infectious mononucleosis and adult Hodgkin's disease (HD): evidence for a specific association with EBV+ve HD in young adults.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Roles of radiation dose, chemotherapy, and hormonal factors in breast cancer following Hodgkin's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Concordance for Hodgkin's disease in identical twins suggesting genetic susceptibility to the young-adult form of the disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268499

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21037568

12 December 2020

inferred from PubMed ID database lookup

A Wilcoxon-type test for trend

1 reference

https://pubmed.ncbi.nlm.nih.gov/21037568

12 December 2020

inferred from PubMed ID database lookup

A clinical and epidemiological study of human leukocyte antigen-DPB alleles in Hodgkin's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21037568

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.696

1 reference

1 reference

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