GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation (Q24569631)

Nature Reviews Immunology

Europe PubMed Central

title

GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation (English)

0 references

1 reference

I-Cheng Ho

1

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Tzong-Shyuan Tai

series ordinal

2

0 references

Sung-Yun Pai

series ordinal

3

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language of work or name

English

0 references

publication date

February 2009

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published in

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volume

9

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issue

2

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page(s)

125-35

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cites work

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27 September 2017

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Critical functions for c-Myb at three checkpoints during thymocyte development

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27 September 2017

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27 September 2017

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An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines

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30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

30 May 2018

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19 June 2018

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Notch signaling is necessary for GATA3 function in the initiation of T cell development.

28 November 2018

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CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

28 November 2018

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28 November 2018

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Interaction between GATA-3 and the transcriptional coregulator Pias1 is important for the regulation of Th2 immune responses

28 November 2018

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28 November 2018

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The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.

28 November 2018

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Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.

28 November 2018

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28 November 2018

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GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Enforced expression of GATA-3 severely reduces human thymic cellularity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Regulation of lineage commitment distinct from positive selection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998182

GATA-3 Promotes Maturation, IFN-γ Production, and Liver-Specific Homing of NK Cells

28 November 2018

1 reference

A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells

31 March 2020

1 reference

Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter

31 March 2020

1 reference

Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus

31 March 2020

1 reference

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

31 March 2020

1 reference

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

31 March 2020

1 reference

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

31 March 2020

1 reference

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level

31 March 2020

1 reference

Long-range intrachromosomal interactions in the T helper type 2 cytokine locus

31 March 2020

1 reference

Stat5 activation plays a critical role in Th2 differentiation

31 March 2020

1 reference

Cutting edge: the differential involvement of the N-finger of GATA-3 in chromatin remodeling and transactivation during Th2 development

31 March 2020

1 reference

Critical YxKxHxxxRP motif in the C-terminal region of GATA3 for its DNA binding and function

31 March 2020

1 reference

Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2476

1 reference

1 reference

1 reference

PubMed publication ID

19151747

1 reference