Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis (Q28943553)

7

0 references

André Uitterlinden

19

0 references

Fernando Rivadeneira

14

0 references

Kenneth Muir

12

Kenneth Muir

1 reference

14 March 2017

Frederic Cailotto

2

0 references

Marjolein J Peters

Marjolein J. Peters

13

0 references

Weiya Zhang

Weiya Zhang

16

0 references

Michael Doherty

Michael Doherty

20

0 references

Joyce B J van Meurs

23

Martha Cecilia Castano-Betancourt

Joyce B. J. van Meurs

1 reference

14 March 2017

18

Tim D. Spector

1 reference

14 March 2017

9

Rose A. Maciewicz

1 reference

14 March 2017

17

Nigel Arden

1 reference

14 March 2017

21

Rik J. U. Lories

1 reference

14 March 2017

22

Ana M. Valdes

1 reference

14 March 2017

11

Sarah Metrustry

1 reference

14 March 2017

1

Martha C. Castaño Betancourt

1 reference

14 March 2017

8

Frank P. Luyten

1 reference

14 March 2017

5

Sally A. Doherty

1 reference

14 March 2017

Hanneke J. Kerkhof

3

1 reference

14 March 2017

Frederique M. F. Cornelis

4

1 reference

14 March 2017

Deborah J. Hart

6

1 reference

14 March 2017

Maggie Wheeler

Proceedings of the National Academy of Sciences of the United States of America

15

1 reference

14 March 2017

language of work or name

English

0 references

publication date

22 May 2012

1 reference

14 March 2017

1 reference

14 March 2017

109

1 reference

14 March 2017

8218–8223

1 reference

14 March 2017

21

1 reference

14 March 2017

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Hundreds of variants clustered in genomic loci and biological pathways affect human height

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Meta-analysis of association between the ASPN D-repeat and osteoarthritis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

A human chondrodysplasia due to a mutation in a TGF-beta superfamily member

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

A variant in MCF2L is associated with osteoarthritis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

DOT1L regulates dystrophin expression and is critical for cardiac function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Early mammalian erythropoiesis requires the Dot1L methyltransferase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Wnt signaling and osteoarthritis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Characterization of the grappa gene, the Drosophila histone H3 lysine 79 methyltransferase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Risk factors for osteoarthritis: genetics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

An overview of real-time quantitative PCR: applications to quantify cytokine gene expression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Assessment of primary hip osteoarthritis: comparison of radiographic methods using colon radiographs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Quantitative measurement of joint space narrowing progression in hip osteoarthritis: a longitudinal retrospective study of patients treated by total hip arthroplasty.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Joint space width measures cartilage thickness in osteoarthritis of the knee: high resolution plain film and double contrast macroradiographic investigation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

The additive effect of individual genes in predicting risk of knee osteoarthritis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Quantification of progressive joint space narrowing in osteoarthritis of the hip: longitudinal analysis of the contralateral hip after total hip arthroplasty.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361426

Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society. Results from a workshop

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22566624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22566624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1119899109

1 reference

561392

ADS bibcode

2012PNAS..109.8218C

0 references

561392

1 reference

1 reference

1 reference