GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease (Q29417137)

16 April 2017

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease (English)

1 reference

genome-wide association study

16 April 2017

0 references

1 reference

0 references

Margaret A. Pericak-Vance

29

Margaret A Pericak-Vance

0 references

Matthew Bailey

Matthew Bailey

12

0 references

Celeste M Karch

Celeste M Karch

6

0 references

Bruno A Benitez

Bruno A Benitez

7

0 references

Denise Harold

Denise Harold

19

0 references

Carlos Cruchaga

Carlos Cruchaga

1

0 references

Alison Goate

Alison M Goate

40

0 references

Lindsay A. Farrer

Lindsay A Farrer

30

0 references

John Q. Trojanowski

26

John Q Trojanowski

1 reference

16 April 2017

35

David M Holtzman

1 reference

16 April 2017

Sheng Chih Jin

4

0 references

Richard Mayeux

28

Richard Mayeux

1 reference

Alzheimer's Disease Neuroimaging Initiative

16 April 2017

38

Alzheimer’s Disease Neuroimaging Initiative (ADNI)

1 reference

16 April 2017

17

David A Bennett

1 reference

16 April 2017

36

John C Morris

1 reference

16 April 2017

34

Anne M Fagan

1 reference

16 April 2017

27

Jonathan L Haines

1 reference

16 April 2017

15

Philip L De Jager

1 reference

16 April 2017

25

Leslie M Shaw

1 reference

16 April 2017

2

John S K Kauwe

1 reference

16 April 2017

14

Joshua M Shulman

1 reference

16 April 2017

33

Douglas Galasko

1 reference

16 April 2017

3

Oscar Harari

1 reference

16 April 2017

5

Yefei Cai

1 reference

16 April 2017

10

David Carrell

1 reference

16 April 2017

11

Sarah Bertelsen

1 reference

16 April 2017

16

Lori Chibnik

1 reference

16 April 2017

Vivianna M Van Deerlin

23

Vivianna M Van Deerlin

1 reference

16 April 2017

32

Elaine R Peskind

1 reference

Alzheimer's Disease Genetics Consortium (ADGC)

16 April 2017

39

Alzheimer Disease Genetic Consortium (ADGC)

1 reference

16 April 2017

Gerard D Schellenberg

31

Gerard D Schellenberg

1 reference

16 April 2017

21

Amy Gerrish

1 reference

16 April 2017

9

Tara Skorupa

1 reference

16 April 2017

37

GERAD Consortium

1 reference

16 April 2017

24

Virginia M-Y Lee

1 reference

16 April 2017

8

Amanda T Jeng

1 reference

16 April 2017

David McKean

13

1 reference

16 April 2017

Steve E Arnold

18

1 reference

16 April 2017

Rebecca Sims

20

1 reference

16 April 2017

Julie Williams

22

1 reference

16 April 2017

language of work or name

English

0 references

publication date

4 April 2013

1 reference

16 April 2017

1 reference

16 April 2017

78

1 reference

16 April 2017

256-268

1 reference

16 April 2017

2

1 reference

TREM2 Variants in Alzheimer's Disease

16 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Principal components analysis corrects for stratification in genome-wide association studies

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Can Alzheimer disease be a form of type 3 diabetes?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Targeting post-translational modifications on tau as a therapeutic strategy for Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

A genome-wide scan for common variants affecting the rate of age-related cognitive decline

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Mechanisms of tau self-aggregation and neurotoxicity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Biomarkers in frontotemporal lobar degenerations--progress and challenges

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Genome partitioning of genetic variation for complex traits using common SNPs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Validating predicted biological effects of Alzheimer's disease associated SNPs using CSF biomarker levels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Relationships between biomarkers in aging and dementia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

The neuropathology of older persons with and without dementia from community versus clinic cohorts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Genetic control of human brain transcript expression in Alzheimer disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Cortical atrophy and language network reorganization associated with a novel progranulin mutation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

One-stage design is empirically more powerful than two-stage design for family-based genome-wide association studies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Study designs for genome-wide association studies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Multistage designs in the genomic era: providing balance in complex disease studies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Effect of truncated-ApoE4 overexpression on tau phosphorylation in cultured N2a cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

MRI and CSF studies in the early diagnosis of Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Novel GLIS3 mutations demonstrate an extended multisystem phenotype.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Biochemical markers in persons with preclinical familial Alzheimer disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

A survey of genetic human cortical gene expression

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Increasing CSF phospho-tau levels during cognitive decline and progression to dementia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Amyloid beta 38, 40, and 42 species in cerebrospinal fluid: more of the same?

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Cerebrospinal fluid tau, Abeta1-42 and inflammatory cytokines in patients with Alzheimer's disease and vascular dementia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3664945

Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3β identified by nano-electrospray mass spectrometry

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23562540

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2013.02.026

1 reference

418737

418737

1 reference

1 reference

1 reference