Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase (Q29568309)

25 April 2017

Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase (English)

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25 April 2017

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5

Guo Jun Chen

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25 April 2017

4

Geoffrey Tison

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25 April 2017

Julia Xu

1

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25 April 2017

Jong Eun Yeon

2

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25 April 2017

Howard Chang

3

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25 April 2017

Jack Wands

6

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25 April 2017

Suzanne de la Monte

7

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25 April 2017

language of work or name

English

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publication date

16 April 2003

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Journal of Biological Chemistry

25 April 2017

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25 April 2017

278

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25 April 2017

29

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26929-26937

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Brain malformations related to prenatal exposure to ethanol

25 April 2017

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Regional differences in cell loss associated with binge-like alcohol exposure during the first two trimesters equivalent in the rat.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Alcohol exposure alters the expression pattern of neural cell adhesion molecules during brain development.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol-induced apoptotic neurodegeneration in the developing brain.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Chronic prenatal ethanol exposure alters the normal ontogeny of choline acetyltransferase activity in the rat septohippocampal system.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol inhibits development of dendrites and synapses in rat hippocampal pyramidal neuron cultures.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol-exposed central neurons fail to migrate and undergo apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Mitochondrial dna damage and impaired mitochondrial function contribute to apoptosis of insulin-stimulated ethanol-exposed neuronal cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Chronic gestational exposure to ethanol impairs insulin-stimulated survival and mitochondrial function in cerebellar neurons

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Insulin receptors in the mammalian central nervous system: binding characteristics and subunit structure

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Intrinsic kinase activity of the insulin receptor.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

The IRS-1 signaling system

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Caspase cleavage enhances the apoptosis-inducing effects of BAD.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Mitochondria and cell death.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Mitochondrial permeability transition in apoptosis and necrosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Altered Purkinje cell maturation in rats exposed prenatally to ethanol. I. Cytology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Multiple insulin-responsive elements regulate transcription of the GAPDH gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Effect of in utero ethanol exposure on the postnatal ontogeny of insulin-like growth factor-1, and type-1 and type-2 insulin-like growth factor receptors in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Facilitative glucose transporters

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Effects of ethanol ingestion on glucose transporter-1 protein and mRNA levels in rat brain.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Differential effects of ethanol on insulin-like growth factor-I receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Inhibition of insulin-like growth factor-1 receptor and IRS-2 signaling by ethanol in SH-SY5Y neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M300401200

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

21 January 2018

1 reference

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The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes

21 January 2018

1 reference

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PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Inhibition of Insulin-Like Growth Factor-I Signaling by Ethanol in Neuronal Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Characterization of Insulin-Like Growth Factor Receptors in Rat Anterior Pituitary, Hypothalamus, and Brain*

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Blood ethanol levels in sober alcohol users seen in an emergency room

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Ethanol inhibition of insulin signaling in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Growth factor-mediated neural proliferation: target of ethanol toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

Effects of ethanol on glucose transporter expression in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300401200

21 January 2018

Identifiers

DOI

10.1074/JBC.M300401200

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25 April 2017

1 reference