Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions (Q29614216)

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10 January 2020

title

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions (English)

2 references

PubMed

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30 April 2017

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10 January 2020

0 references

Panagiotis Karakaidos

3

1 reference

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10 January 2020

author name string

Vassilis G Gorgoulis

1

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10 January 2020

Leandros-Vassilios F Vassiliou

2

1 reference

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10 January 2020

Panayotis Zacharatos

4

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10 January 2020

Athanassios Kotsinas

5

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10 January 2020

Triantafillos Liloglou

6

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10 January 2020

Monica Venere

7

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10 January 2020

Richard A Ditullio

8

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10 January 2020

Nikolaos G Kastrinakis

9

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10 January 2020

Brynn Levy

10

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10 January 2020

Dimitris Kletsas

11

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10 January 2020

Akihiro Yoneta

12

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10 January 2020

Meenhard Herlyn

13

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10 January 2020

Christos Kittas

14

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10 January 2020

Thanos D Halazonetis

15

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language of work or name

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30 April 2017

publication date

1 April 2005

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10 January 2020

2 references

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10 January 2020

volume

434

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30 April 2017

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10 January 2020

page(s)

907-913

1 reference

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10 January 2020

issue

7035

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30 April 2017

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Cell-cycle checkpoints and cancer

10 January 2020

cites work

1 reference

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DNA damage foci at dysfunctional telomeres

1 May 2017

1 reference

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A DNA damage checkpoint response in telomere-initiated senescence

1 May 2017

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 May 2017

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 May 2017

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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

1 May 2017

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 May 2017

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ATR and ATRIP: partners in checkpoint signaling

1 May 2017

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ATR Regulates Fragile Site Stability

1 May 2017

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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

1 May 2017

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p53 mutations in human cancers

1 May 2017

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Constitutively active DNA damage checkpoint pathways as the driving force for the high frequency of p53 mutations in human cancer

21 January 2018

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Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression

21 January 2018

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Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional contro

21 January 2018

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Chk1 and Chk2 kinases in checkpoint control and cancer

21 January 2018

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53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

21 January 2018

1 reference

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

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Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B.

21 January 2018

1 reference

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Deregulated cyclin E induces chromosome instability

21 January 2018

1 reference

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Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation

21 January 2018

1 reference

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A p53-dependent checkpoint pathway prevents rereplication

21 January 2018

1 reference

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Deregulation of cyclin E in human cells interferes with prereplication complex assembly

21 January 2018

1 reference

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Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells

21 January 2018

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21 January 2018

Common fragile sites.

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High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss

21 January 2018

1 reference

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The yeast CDK inhibitor Sic1 prevents genomic instability by promoting replication origin licensing in late G(1)

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03485

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

3 references

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30 April 2017

Consolidated OpenCitations Corpus – April 2017

146519

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Dimensions Publication ID

10 January 2020

1005294665

0 references

146519

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15829965

3 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

146519

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