The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis (Q29622875)

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Liang J

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Shao SH

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Xu ZX

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Hennessy B

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Ding Z

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Larrea M

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Kondo S

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Dumont DJ

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Gutterman JU

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Walker CL

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Slingerland JM

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Mills GB

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language of work or name

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publication date

February 2007

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volume

9

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page(s)

218-24

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issue

2

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A Restriction Point for Control of Normal Animal Cell Proliferation

30 April 2017

cites work

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Upstream and downstream of mTOR

1 May 2017

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Growth factor regulation of autophagy and cell survival in the absence of apoptosis

1 May 2017

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TSC2 mediates cellular energy response to control cell growth and survival

1 May 2017

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 May 2017

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C-terminal phosphorylation controls the stability and function of p27kip1

1 May 2017

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 May 2017

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Inhibition of autophagy in mitotic animal cells

1 May 2017

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

1 May 2017

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

1 May 2017

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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

1 May 2017

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Nutrient-regulated protein kinases in budding yeast

1 May 2017

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7 January 2021

The AMP-activated protein kinase pathway--new players upstream and downstream.

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The role of autophagy in cancer development and response to therapy.

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Autophagy in metazoans: cell survival in the land of plenty

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7 January 2021

Autophagosomes: biogenesis from scratch?

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7 January 2021

G1 cell-cycle control and cancer

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7 January 2021

Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity

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7 January 2021

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

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7 January 2021

Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization

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7 January 2021

Phosphorylation of p27Kip1 at Threonine 198 by p90 Ribosomal Protein S6 Kinases Promotes Its Binding to 14-3-3 and Cytoplasmic Localization

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7 January 2021

Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization

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7 January 2021

Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

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7 January 2021

Autophagic fungal cell death is necessary for infection by the rice blast fungus.

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7 January 2021

Isoform-specific purification and substrate specificity of the 5'-AMP-activated protein kinase

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7 January 2021

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

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7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

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7 January 2021

ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells

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7 January 2021

A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis.

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7 January 2021

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

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7 January 2021

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades

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7 January 2021

Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.

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7 January 2021

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Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2025740

1045284002

0 references

2025740

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=17237771

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017