Meiotic 41 Dmel_CG4252 (Q29817240)

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Protein found in Drosophila melanogaster

CG4252-PA
drosophila ATR
CG4252 gene product from transcript CG4252-RA
ATM-RAD3 related
mei-41-PA
meiotic 41
mei-41
meiotic-41
ataxia telangiectasia and Rad3 related

Language	Label	Description	Also known as
English	Meiotic 41 Dmel_CG4252	Protein found in Drosophila melanogaster	CG4252-PA drosophila ATR CG4252 gene product from transcript CG4252-RA ATM-RAD3 related mei-41-PA meiotic 41 mei-41 meiotic-41 ataxia telangiectasia and Rad3 related

Statements

1 reference

25 May 2022

UniProt protein ID

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

Armadillo-type fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PIK-related kinase, FAT family

1 reference

based on heuristic

inferred from protein domain or family

PIK-related kinase family

1 reference

based on heuristic

inferred from protein domain or family

FATC domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

UME domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Phosphatidylinositol 3/4-kinase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

protein kinase activity

determination method

1 reference

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

protein serine/threonine kinase activity

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

kinase activity

determination method

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

protein serine/threonine kinase activity

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

determination method

biological process

DNA replication checkpoint signaling

determination method

1 reference

8 April 2019

Drosophila dCBP is involved in establishing the DNA replication checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

DNA damage checkpoint signaling

determination method

3 references

21 June 2018

DNA repair in Drosophila: insights from the Drosophila genome sequence.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VXG8&geneProductId=UniProtKB:Q9VXG8

determination method

21 June 2018

Drosophila ATR in double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VXG8&geneProductId=UniProtKB:Q9VXG8

determination method

21 June 2018

mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VXG8&geneProductId=UniProtKB:Q9VXG8

determination method

meiotic DNA double-strand break processing

determination method

1 reference

8 April 2019

Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

telomere maintenance

determination method

1 reference

21 June 2018

Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VXG8&geneProductId=UniProtKB:Q9VXG8

determination method

embryonic development via the syncytial blastoderm

determination method

1 reference

8 April 2019

Cell-cycle checkpoint kinases: checking in on the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

double-strand break repair

determination method

1 reference

8 April 2019

Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

protein phosphorylation

determination method

1 reference

8 April 2019

Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

regulation of mitotic nuclear division

determination method

3 references

8 April 2019

Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

mitotic cell cycle checkpoint signaling

determination method

1 reference

31 January 2018

Cell-cycle checkpoint kinases: checking in on the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VXG8&geneProductId=UniProtKB:Q9VXG8

determination method

reciprocal meiotic recombination

determination method

3 references

8 April 2019

Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

mei-41 is required for precocious anaphase in Drosophila females

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

regulation of syncytial blastoderm mitotic cell cycle

determination method

1 reference

8 April 2019

mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

cellularization

determination method

1 reference

8 April 2019

Cell-cycle checkpoint kinases: checking in on the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

imaginal disc development

determination method

1 reference

8 April 2019

Cell-cycle checkpoint kinases: checking in on the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

response to radiation

determination method

1 reference

8 April 2019

Cell-cycle checkpoint kinases: checking in on the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

female meiosis chromosome segregation

determination method

1 reference

8 April 2019

Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

peptidyl-serine phosphorylation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

chromosome condensation

determination method

1 reference

8 April 2019

Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

oocyte fate determination

determination method

1 reference

8 April 2019

Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

response to caffeine

determination method

1 reference

8 April 2019

The Smc5/Smc6/MAGE complex confers resistance to caffeine and genotoxic stress in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

mitotic DNA replication checkpoint signaling

determination method

1 reference

8 April 2019

Drosophila Claspin is required for the G2 arrest that is induced by DNA replication stress but not by DNA double-strand breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

double-strand break repair via single-strand annealing

determination method

1 reference

8 April 2019

Drosophila ATR in double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

double-strand break repair via synthesis-dependent strand annealing

determination method

1 reference

8 April 2019

Drosophila ATR in double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

cellular response to DNA damage stimulus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

DNA damage checkpoint signaling

determination method

4 references

8 April 2019

DNA repair in Drosophila: insights from the Drosophila genome sequence.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

Drosophila ATR in double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VXG8

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

Phosphatidylinositol 3-/4-kinase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

PIK-related kinase, FAT

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

PIK-related kinase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

Phosphatidylinositol 3/4-kinase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VXG8

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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