Cell-cycle checkpoint kinases: checking in on the cell cycle (Q34076838)

30 July 2017

1 reference

title

Cell-cycle checkpoint kinases: checking in on the cell cycle (English)

1 reference

14-3-3epsilon Dmel_CG31196

30 July 2017

1 reference

Grapes Dmel_CG17161

1 reference

Mutagen-sensitive 304 Dmel_CG7347

1 reference

Meiotic 41 Dmel_CG4252

1 reference

author name string

N C Walworth

series ordinal

1

1 reference

PubMed ID

11063934

30 July 2017

language of work or name

1 reference

1 December 2000

1 reference

Current Opinion in Cell Biology

30 July 2017

1 reference

30 July 2017

12

1 reference

30 July 2017

6

1 reference

30 July 2017

697-704

1 reference

Checkpoints: controls that ensure the order of cell cycle events

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The G2-phase DNA-damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Activating the DNA damage checkpoint in a developmental context.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Initiation of genetic recombination and recombination-dependent replication

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Replication fork arrest and DNA recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The Mre11 complex and ATM: collaborating to navigate S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Sensing and responding to DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Regulation of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Substrate specificities and identification of putative substrates of ATM kinase family members

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Drosophila p53 binds a damage response element at the reaper locus

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Identification and characterization of a p53 homologue in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Checkpoints on the road to mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

A kinase from fission yeast responsible for blocking mitosis in S phase.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Regulation of DNA-replication origins during cell-cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Ataxia-telangiectasia and the ATM gene: linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

DNA-replication checkpoint control at the Drosophila midblastula transition

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The Drosophila grapes gene is related to checkpoint gene chk1/rad27 and is required for late syncytial division fidelity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Histone H1 dephosphorylation is mediated through a radiation-induced signal transduction pathway dependent on ATM.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Mechanism by which caffeine potentiates lethality of nitrogen mustard

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Caffeine inhibits the checkpoint kinase ATM

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

DNA polymerase delta is required for the replication feedback control of cell cycle progression in Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The S / M checkpoint at 37˚C and the recovery of viability of the mutant pol δ ts3 require the crb2 + /rhp9 + gene in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

The Pds1 anaphase inhibitor and Mec1 kinase define distinct checkpoints coupling S phase with mitosis in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

Mutational effect of fission yeast polalpha on cell cycle events

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900154-X

7 January 2021

10.1016/S0955-0674(00)00154-X

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11063934