Merlin Dmel_CG14228 (Q29819518)

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Protein found in Drosophila melanogaster
  • CG14228-PB
  • D merlin
  • dmerlin
  • Ezrin-moesin-radixin-2
  • BG01543
  • Mer-PA
  • Merlin/Neurofibromin 2
  • merlin
  • Mer-PB
  • CG14228-PA
  • CG14228 gene product from transcript CG14228-RB
  • Mer
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Language Label Description Also known as
English
Merlin Dmel_CG14228
Protein found in Drosophila melanogaster
  • CG14228-PB
  • D merlin
  • dmerlin
  • Ezrin-moesin-radixin-2
  • BG01543
  • Mer-PA
  • Merlin/Neurofibromin 2
  • merlin
  • Mer-PB
  • CG14228-PA
  • CG14228 gene product from transcript CG14228-RB
  • Mer

Statements

molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
GOA
curator
UniProt
UniProt protein ID
Q24564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IPI
retrieved
8 April 2019
stated in
Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin
GOA
curator
UniProt
UniProt protein ID
Q24564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IPI
retrieved
8 April 2019
stated in
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IPI
retrieved
8 April 2019
stated in
Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IPI
retrieved
8 April 2019
stated in
The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IPI
cell component
biological process
negative regulation of cell population proliferation
determination method
IEA
IGI
IMP
6 references
retrieved
8 April 2019
stated in
The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IMP
retrieved
8 April 2019
stated in
The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IMP
retrieved
8 April 2019
stated in
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IMP
retrieved
8 April 2019
stated in
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IGI
retrieved
8 April 2019
stated in
The neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IGI
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IEA
positive regulation of hippo signaling
determination method
IDA
IGI
IMP
6 references
retrieved
8 April 2019
stated in
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
GOA
curator
UniProt
UniProt protein ID
Q24564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IMP
retrieved
8 April 2019
stated in
The WW domain protein Kibra acts upstream of Hippo in Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IMP
retrieved
8 April 2019
stated in
In vivo regulation of Yorkie phosphorylation and localization.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IGI
retrieved
8 April 2019
stated in
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IGI
retrieved
8 April 2019
stated in
The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IGI
retrieved
8 April 2019
stated in
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24564
determination method
IDA

Identifiers

 
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