Linker length matters, fynomer-Fc fusion with an optimized linker displaying picomolar IL-17A inhibition potency (Q30009438)

21 May 2017

title

Linker length matters, fynomer-Fc fusion with an optimized linker displaying picomolar IL-17A inhibition potency (English)

1 reference

21 May 2017

Michela Silacci

1

1 reference

21 May 2017

Nadja Baenziger-Tobler

2

1 reference

21 May 2017

Wibke Lembke

3

1 reference

21 May 2017

Wenjuan Zha

4

1 reference

21 May 2017

Sarah Batey

5

1 reference

21 May 2017

Julian Bertschinger

6

1 reference

21 May 2017

Dragan Grabulovski

7

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21 May 2017

language of work or name

English

0 references

publication date

1 April 2014

1 reference

Journal of Biological Chemistry

21 May 2017

published in

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21 May 2017

volume

289

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21 May 2017

issue

20

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21 May 2017

page(s)

14392-14398

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Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones

21 May 2017

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22 May 2017

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Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

22 May 2017

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22 May 2017

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22 May 2017

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22 May 2017

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22 May 2017

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22 May 2017

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

21 January 2018

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Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis

21 January 2018

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21 January 2018

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21 January 2018

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High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

26 November 2018

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12 December 2020

An investigation of oligopeptides linking domains in protein tertiary structures and possible candidates for general gene fusion

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12 December 2020

Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists

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12 December 2020

Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1074/JBC.M113.534578

1 reference

21 May 2017

0 references

1 reference