GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells (Q30010072)

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scientific article published on 26 July 2012

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English	GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells	scientific article published on 26 July 2012

Statements

scholarly article

1 reference

Europe PubMed Central

21 May 2017

GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells (English)

1 reference

Europe PubMed Central

21 May 2017

0 references

colon carcinoma

1 reference

based on heuristic

inferred from title

author name string

Hao Zhang

1

1 reference

Europe PubMed Central

21 May 2017

Shenghua Zhang

2

1 reference

Europe PubMed Central

21 May 2017

Hongwei He

3

1 reference

Europe PubMed Central

21 May 2017

Wuli Zhao

4

1 reference

Europe PubMed Central

21 May 2017

Jianhua Chen

5

1 reference

Europe PubMed Central

21 May 2017

Rong-guang Shao

6

1 reference

Europe PubMed Central

21 May 2017

publication date

26 July 2012

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Europe PubMed Central

21 May 2017

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Europe PubMed Central

21 May 2017

103

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Europe PubMed Central

21 May 2017

10

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Europe PubMed Central

21 May 2017

1848-1856

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Europe PubMed Central

21 May 2017

A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02361.X

21 January 2018

Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02361.X

21 January 2018

A Ras-GTPase-activating protein SH3-domain-binding protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2012.02361.X

21 January 2018

Suppression of N-Ras by shRNA-expressing plasmid increases sensitivity of HepG2 cells to vincristine-induced growth inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GEFs and GAPs: critical elements in the control of small G proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockage of NF-kappaB by IKKbeta- or RelA-siRNA rather than the NF-kappaB super-suppressor IkappaBalpha mutant potentiates adriamycin-induced cytotoxicity in lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological and chemical inhibitors of NF-kappaB sensitize SiHa cells to cisplatin-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of Ras-GTPase activating protein SH3 domain-binding proteins, G3BPs, in human breast cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular CD24 inhibits cell invasion by posttranscriptional regulation of BART through interaction with G3BP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RasGAP-associated endoribonuclease G3BP assembles stress granules

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based design of peptides against G3BP with cytotoxicity on tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-R1 signaling: a beautiful pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappa B p65 transactivation domain is involved in the NF-kappa B-inducing kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N-terminal domain of G3BP enhances cell motility and invasion by posttranscriptional regulation of BART.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of specific protein expression levels by PTEN: identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of G3BPs: tissue specific expression, chromosomal localisation and rasGAP(120) binding studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G3BP is overexpressed in human tumors and promotes S phase entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kB in development and progression of human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing complexity of Ras signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RasGAP-derived peptide 38GAP potentiates the cytotoxicity of cisplatin through inhibitions of Akt, ERK and NF-κB in colon carcinoma HCT116 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concurrent blockade of the NF-kappaB and Akt pathways potently sensitizes cancer cells to chemotherapeutic-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAS pathways to cell cycle control and cell transformation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22703643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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