Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions (Q30159819)

8 June 2017

Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions (English)

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8 June 2017

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Glenn F King

3

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Elizabeth A. Eipper

5

object named as

Betty A Eipper

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8 June 2017

Martin R Schiller

1

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8 June 2017

Kausik Chakrabarti

2

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8 June 2017

Noraisha I Schiller

4

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8 June 2017

Mark W Maciejewski

6

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8 June 2017

language of work or name

English

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publication date

27 April 2006

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Journal of Biological Chemistry

8 June 2017

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8 June 2017

281

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8 June 2017

27

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8 June 2017

18774-18786

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

8 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Autoinhibition mechanism of proto-Dbl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Functional analysis of the Caenorhabditis elegans UNC-73B PH domain demonstrates a role in activation of the Rac GTPase in vitro and axon guidance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Distinct expression patterns and transforming properties of multiple isoforms of Ost, an exchange factor for RhoA and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Regulatory intramolecular association in a tyrosine kinase of the Tec family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Intermolecular interactions between the SH3 domain and the proline-rich TH region of Bruton's tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

An intramolecular SH3-domain interaction regulates c-Abl activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

A specific intermolecular association between the regulatory domains of a Tec family kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

21 January 2018

Autoinhibition of c-Abl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Molecular basis of phosphorylation-induced activation of the NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Torsion angle dynamics for NMR structure calculation with the new program DYANA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Induction of lamellipodia by Kalirin does not require its guanine nucleotide exchange factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Protein structure comparison by alignment of distance matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Pseudomonas cellulose-binding domains mediate their effects by increasing enzyme substrate proximity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Intramolecular binding of a proximal PPII helix to an SH3 domain in the fusion protein SH3Hck : PPIIhGAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

A RHO GTPase-mediated pathway is required during P cell migration in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

v-Crk modulation of growth factor-induced PC12 cell differentiation involves the Src homology 2 domain of v-Crk and sustained activation of the Ras/mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Crk family adaptors-signalling complex formation and biological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Targeted expression of an oncogenic adaptor protein v-Crk potentiates axonal growth in dorsal root ganglia and motor neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The identification of conserved interactions within the SH3 domain by alignment of sequences and structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Novel recognition mode between Vav and Grb2 SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Ligand-induced changes in dynamics in the RT loop of the C-terminal SH3 domain of Sem-5 indicate cooperative conformational coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The ScPex13p SH3 domain exposes two distinct binding sites for Pex5p and Pex14p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Intersectin 1L guanine nucleotide exchange activity is regulated by adjacent src homology 3 domains that are also involved in endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Effect of Fgd1 on cortactin in Arp2/3 complex-mediated actin assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The SH3 domain of Eps8 exists as a novel intertwined dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Critical role for Kalirin in nerve growth factor signaling through TrkA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Purification and characterization of PAM-1, an integral membrane protein involved in peptide processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

An isoform of kalirin, a brain-specific GDP/GTP exchange factor, is enriched in the postsynaptic density fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

Calcium binding induces interaction between the N- and C-terminal domains of yeast calmodulin and modulates its overall conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512482200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512482200

1 reference

8 June 2017

1 reference