Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction (Q30165054)

9 June 2017

title

Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction (English)

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amyotrophic lateral sclerosis

9 June 2017

main subject

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1

Ashutosh Tiwari

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9 June 2017

Lawrence J Hayward

2

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9 June 2017

language of work or name

English

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publication date

27 November 2002

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Journal of Biological Chemistry

9 June 2017

published in

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9 June 2017

volume

278

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9 June 2017

issue

8

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9 June 2017

page(s)

5984-5992

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Amyotrophic lateral sclerosis

9 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Amyotrophic lateral sclerosis: a proposed mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Differential scanning calorimetry of Cu,Zn-superoxide dismutase, the apoprotein, and its zinc-substituted derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Subunit association and side-chain reactivities of bovine erythrocyte superoxide dismutase in denaturing solvents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

The solution structure of a monomeric, reduced form of human copper,zinc superoxide dismutase bearing the same charge as the native protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Protein disulfide isomerase: multiple roles in the modification of nascent secretory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Making and breaking disulfide bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

How to measure and predict the molar absorption coefficient of a protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Measurement of protein using bicinchoninic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Characterizing closely spaced, complex disulfide bond patterns in peptides and proteins by liquid chromatography/electrospray ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Development of a sensitive assay to detect reversibly oxidized protein cysteine sulfhydryl groups.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Coordination of heavy metals by dithiothreitol, a commonly used thiol group protectant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

A comparison between the sulfhydryl reductants tris(2-carboxyethyl)phosphine and dithiothreitol for use in protein biochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Metabolism and functions of glutathione in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Ascorbate regulation and its neuroprotective role in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

The role of arginine 143 in the electrostatics and mechanism of Cu,Zn superoxide dismutase: computational and experimental evaluation by mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Heterodimeric structure of superoxide dismutase in complex with its metallochaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Amino acid sequence of chicken Cu, Zn-containing superoxide dismutase and identification of glutathionyl adducts at exposed cysteine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Backbone Dynamics of Human Cu,Zn Superoxide Dismutase and of Its Monomeric F50E/G51E/E133Q Mutant: The Influence of Dimerization on Mobility and Function†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Identification of an artifact in the mass spectrometry of proteins derivatized with iodoacetamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

A procedure for quantitative determination of tris(2-carboxyethyl)phosphine, an odorless reducing agent more stable and effective than dithiothreitol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

In vivo formation of Cu,Zn superoxide dismutase disulfide bond in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Stability of mutant superoxide dismutase-1 associated with familial amyotrophic lateral sclerosis determines the manner of copper release and induction of thioredoxin in erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210419200

21 January 2018

Identifiers

DOI

10.1074/JBC.M210419200

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9 June 2017

1 reference