Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis (Q30175843)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074170%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis (English)

1 reference

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11 November 2019

author name string

F M van den Ent

series ordinal

1

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11 November 2019

A Vos

series ordinal

2

1 reference

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11 November 2019

R H Plasterk

series ordinal

3

1 reference

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11 November 2019

language of work or name

1 reference

1 April 1999

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11 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074170%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

73

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11 November 2019

issue

4

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11 November 2019

page(s)

3176-3183

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HIV integrase: a target for drug discovery

11 November 2019

cites work

1 reference

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Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions

3 June 2018

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Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding

3 June 2018

1 reference

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Mutational scan of the human immunodeficiency virus type 2 integrase protein

3 June 2018

1 reference

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Mapping viral DNA specificity to the central region of integrase by using functional human immunodeficiency virus type 1/visna virus chimeric proteins

3 June 2018

1 reference

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Molecular mechanisms in retrovirus DNA integration

3 June 2018

1 reference

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Implication of a central cysteine residue and the HHCC domain of Moloney murine leukemia virus integrase protein in functional multimerization

3 June 2018

1 reference

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Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

3 June 2018

1 reference

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The core domain of HIV-1 integrase recognizes key features of its DNA substrates

3 June 2018

1 reference

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Crystal structure of the specific DNA-binding domain of Tc3 transposase of C.elegans in complex with transposon DNA.

3 June 2018

1 reference

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Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Biochemical characterization of recombinant equine infectious anemia virus integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations

3 June 2018

1 reference

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Retroviral integrases and their cousins

3 June 2018

1 reference

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Coordinated disintegration reactions mediated by Moloney murine leukemia virus integrase

3 June 2018

1 reference

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Zinc stimulates Mg2+-dependent 3'-processing activity of human immunodeficiency virus type 1 integrase in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Identification of amino acids in HIV-2 integrase involved in site-specific hydrolysis and alcoholysis of viral DNA termini

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Complementation between HIV integrase proteins mutated in different domains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Rapid solution assays for retroviral integration reactions and their use in kinetic analyses of wild-type and mutant Rous sarcoma virus integrases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The human immunodeficiency virus integrase protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Activities of the feline immunodeficiency virus integrase protein produced in Escherichia coli.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

3 June 2018

1 reference

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A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

3 June 2018

1 reference

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Characterization of recombinant murine leukemia virus integrase.

3 June 2018

1 reference

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DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.

3 June 2018

1 reference

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Characterization of the minimal DNA-binding domain of the HIV integrase protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

3 June 2018

1 reference

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Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations

3 June 2018

1 reference

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Bacterial transposases and retroviral integrases.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Recombining the structures of HIV integrase, RuvC and RNase H.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Structural domains of IS10 transposase and reconstitution of transposition activity from proteolytic fragments lacking an interdomain linker

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Solution structure of the DNA binding domain of HIV-1 integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

3 June 2018

The retroviral enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Crystal structure of trp repressor/operator complex at atomic resolution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Origins and evolutionary relationships of retroviruses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

The N-terminal region of HIV-1 integrase is required for integration activity, but not for DNA-binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Mutational analysis of the integrase protein of human immunodeficiency virus type 2

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Central core domain of retroviral integrase is responsible for target site selection

26 November 2018

1 reference

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Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=104080

Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro

26 November 2018

1 reference

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Tn552, a novel transposable element from Staphylococcus aureus.

26 November 2018

1 reference

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The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc

26 November 2018

1 reference

12 December 2020

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

12 December 2020

The Mu transpositional enhancer can function in trans: Requirement of the enhancer for synapsis but not strand cleavage

1 reference

12 December 2020

Monoclonal antibodies against HIV type 1 integrase: clues to molecular structure

1 reference

12 December 2020

Activities and substrate specificity of the evolutionarily conserved central domain of retroviral integrase

1 reference

12 December 2020

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

1 reference

12 December 2020

10.1128/JVI.73.4.3176-3183.1999

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074170%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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