Molecular mechanisms in retrovirus DNA integration (Q40868886)

24 September 2017

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title

Molecular mechanisms in retrovirus DNA integration (English)

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24 September 2017

Asante-Appiah E

1

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PubMed ID

9477115

24 September 2017

Skalka AM

series ordinal

2

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24 September 2017

1 December 1997

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24 September 2017

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24 September 2017

36

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24 September 2017

3

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24 September 2017

139-156

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Isolation of high-affinity RNA ligands to HIV-1 integrase from a random pool

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Retroviral integrase, putting the pieces together

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A metal-induced conformational change and activation of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Atomic structure of the RuvC resolvase: a holliday junction-specific endonuclease from E. coli

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A nucleoprotein complex mediates the integration of retroviral DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Correct integration of retroviral DNA in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Effect of topoisomerase inhibitors on the in vitro HIV DNA integration reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Mutants and pseudorevertants of Moloney murine leukemia virus with alterations at the integration site

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Hotspots and warm spots: integration specificity of retroelements

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

(-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibitors of human immunodeficiency virus integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

HIV-1 infection of non-dividing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Synergistic inhibition of human immunodeficiency virus type 1 and type 2 replication in vitro by castanospermine and 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Nonrandom integration of retroviral DNA in vitro: effect of CpG methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Activities and substrate specificity of the evolutionarily conserved central domain of retroviral integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibition of human immunodeficiency virus integrase by bis-catechols

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Characterization of Mg(2+)-dependent 3'-processing activity for human immunodeficiency virus type 1 integrase in vitro: real-time kinetic studies using fluorescence resonance energy transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Solution structure of the DNA binding domain of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibition of human immunodeficiency virus type-1 integrase by curcumin

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Zinc binding by retroviral integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Characterization of the human spuma retrovirus integrase by site-directed mutagenesis, by complementation analysis, and by swapping the zinc finger domain of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The terminal nucleotides of retrovirus DNA are required for integration but not virus production

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The metal ion-induced cooperative binding of HIV-1 integrase to DNA exhibits a marked preference for Mn(II) rather than Mg(II).

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Characterization of the minimal DNA-binding domain of the HIV integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Retroviral integrases and their cousins

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Integration of murine leukemia virus DNA depends on mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

3'-end processing and kinetics of 5'-end joining during retroviral integration in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Disruption of the terminal base pairs of retroviral DNA during integration

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A synthetic peptide from the human immunodeficiency virus type-1 integrase exhibits coiled-coil properties and interferes with the in vitro integration activity of the enzyme. Correlated biochemical and spectroscopic results

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Characterization of feline immunodeficiency virus integrase and analysis of functional domains

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Highly preferred targets for retrovirus integration

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

A unified polymerase mechanism for nonhomologous DNA and RNA polymerases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Portals of entry: uncovering HIV nuclear transport pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Efficient concerted integration of retrovirus-like DNA in vitro by avian myeloblastosis virus integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Recombining the structures of HIV integrase, RuvC and RNase H.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Arylamide inhibitors of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2897%2900046-6

7 January 2021

10.1016/S0166-3542(97)00046-6

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9477115