Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations (Q30179386)

16 September 2017

Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations (English)

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Valosin containing protein

16 September 2017

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GOA release 2020-03-11

UBX domain protein 6

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GOA release 2020-03-11

Caveolin 1

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GOA release 2020-03-11

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6

Arnold Hayer

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16 September 2017

13

Ruedi Aebersold

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16 September 2017

Timo Glatter

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Hemmo H Meyer

object named as

Hemmo Meyer

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Robert H Baloh

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object named as

Robert H Baloh

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16 September 2017

Danilo Ritz

1

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16 September 2017

Maja Vuk

2

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Philipp Kirchner

3

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16 September 2017

Monika Bug

4

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Sabina Schütz

5

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Sebastian Bremer

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Caleb Lusk

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Houkeun Lee

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Matthias Gstaiger

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Conrad C Weihl

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7 August 2011

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8

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based on heuristic

inferred from page(s)

published in

Nature Cell Biology

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13

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9

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1116-1123

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describes a project that uses

16 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3246400/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

1 reference

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Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation.

3 June 2018

1 reference

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Imbalances in p97 co-factor interactions in human proteinopathy

3 June 2018

1 reference

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VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Recent advances in understanding the molecular basis of Paget disease of bone

3 June 2018

1 reference

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Valosin-containing protein disease: inclusion body myopathy with Paget's disease of the bone and fronto-temporal dementia

3 June 2018

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UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

3 June 2018

1 reference

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Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease

3 June 2018

1 reference

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Ubxd1 is a novel co-factor of the human p97 ATPase

3 June 2018

1 reference

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DOA1/UFD3 plays a role in sorting ubiquitinated membrane proteins into multivesicular bodies

3 June 2018

1 reference

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UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

3 June 2018

1 reference

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Role(s) of Cdc48/p97 in mitosis.

3 June 2018

1 reference

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The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy

3 June 2018

1 reference

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The multiple faces of caveolae

3 June 2018

1 reference

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A guided tour into subcellular colocalization analysis in light microscopy

3 June 2018

1 reference

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General framework for developing and evaluating database scoring algorithms using the TANDEM search engine

3 June 2018

1 reference

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A uniform proteomics MS/MS analysis platform utilizing open XML file formats

3 June 2018

1 reference

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Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

3 June 2018

1 reference

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Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargo-triggered, vesicular transporters

3 June 2018

1 reference

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Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Distinct monoubiquitin signals in receptor endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Protein dislocation from the endoplasmic reticulum--pulling out the suspect

3 June 2018

1 reference

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Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy

3 June 2018

1 reference

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Caveolin-1 and -2 in the exocytic pathway of MDCK cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Oligomeric structure of caveolin: implications for caveolae membrane organization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246400

Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

3 June 2018

1 reference

A transgenic mouse model for monitoring endoplasmic reticulum stress

21 January 2018

1 reference

Biogenesis of caveolae: stepwise assembly of large caveolin and cavin complexes

21 January 2018

1 reference

Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton

21 January 2018

1 reference

Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.

21 January 2018

1 reference

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NCB2301

1 reference

Dimensions Publication ID

16 September 2017

0 references

1 reference

16 September 2017

1 reference