The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy (Q40157250)

18 September 2017

The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy (English)

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18 September 2017

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18 September 2017

Hanns Lochmüller

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Johnny Kim

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Johnny Kim

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author name string

Philipp Christoph Janiesch

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18 September 2017

Julien Mouysset

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18 September 2017

Roja Barikbin

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18 September 2017

Giuseppe Cassata

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18 September 2017

Sabine Krause

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18 September 2017

18 March 2007

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18 September 2017

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18 September 2017

379-390

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https://scigraph.springernature.com/pub.10.1038/ncb1554

18 September 2017

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cites work

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Cachexia in cancer patients

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What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

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Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis

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Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin

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Temperature-sensitive mutation affecting myofilament assembly in Caenorhabditis elegans

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Unc-45 mutations in Caenorhabditis elegans implicate a CRO1/She4p-like domain in myosin assembly

21 January 2018

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Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

21 January 2018

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Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

21 January 2018

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HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

21 January 2018

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Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

21 January 2018

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

21 January 2018

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

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Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

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A conserved role of Caenorhabditis elegans CDC-48 in ER-associated protein degradation

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Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine-induced protein aggregation.

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ERAD: the long road to destruction

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A trip to the ER: coping with stress

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

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A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response

21 January 2018

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Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

21 January 2018

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A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

21 January 2018

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Maternal UNC-45 is involved in cytokinesis and colocalizes with non-muscle myosin in the early Caenorhabditis elegans embryo

21 January 2018

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Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

21 January 2018

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Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions

21 January 2018

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

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The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis

21 January 2018

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Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a

21 January 2018

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Mammalian E4 is required for cardiac development and maintenance of the nervous system

21 January 2018

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The UCS family of myosin chaperones

21 January 2018

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Autosomal dominant myopathy: missense mutation (Glu-706 --> Lys) in the myosin heavy chain IIa gene

21 January 2018

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Mutations and sequence variation in the human myosin heavy chain IIa gene (MYH2)

21 January 2018

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Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

21 January 2018

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7 January 2021

Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts

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7 January 2021

A Major Conformational Change in p97 AAA ATPase upon ATP Binding

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7 January 2021

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

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7 January 2021

The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis

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7 January 2021

Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation

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7 January 2021

Identifiers

DOI

10.1038/NCB1554

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18 September 2017

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