Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD. (Q30234466)

11 June 2017

1 reference

title

Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD. (English)

1 reference

11 June 2017

cardiovascular disease

1 reference

inferred from title

author

Kamyar Kalantar-Zadeh

3

Kamyar Kalantar-Zadeh

0 references

Per Magnusson

Per Magnusson

5

0 references

Mathias Haarhaus

Mathias Haarhaus

1

0 references

Peter Stenvinkel

4

Peter Stenvinkel

1 reference

11 June 2017

Vincent Brandenburg

2

1 reference

PubMed ID

28502983

11 June 2017

language of work or name

English

0 references

publication date

15 May 2017

1 reference

Nature Reviews Nephrology

11 June 2017

1 reference

Chronic kidney disease: a public health priority and harbinger of premature cardiovascular disease

11 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Renin-Angiotensin System Inhibitors and Kidney and Cardiovascular Outcomes in Patients With CKD: A Bayesian Network Meta-analysis of Randomized Clinical Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Chronic kidney disease: a clinical model of premature aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Chronic kidney disease and premature ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Chronic kidney disease and cardiovascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Can serum levels of alkaline phosphatase and phosphate predict cardiovascular diseases and total mortality in individuals with preserved renal function? A systemic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Circulating calcium concentrations, vascular disease and mortality: a systematic review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Differences in sialic acid residues among bone alkaline phosphatase isoforms: a physical, biochemical, and immunological characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Glycosylation differences contribute to distinct catalytic properties among bone alkaline phosphatase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Biology of human alkaline phosphatases with special reference to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Structural evidence for a functional role of human tissue nonspecific alkaline phosphatase in bone mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Zinc deprivation inhibits extracellular matrix calcification through decreased synthesis of matrix proteins in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Functional significance of calcium binding to tissue-nonspecific alkaline phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Alkaline phosphatase is an ectoenzyme that acts on micromolar concentrations of natural substrates at physiologic pH in human osteosarcoma (SAOS-2) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

The glycosyl-phosphatidylinositol anchor of membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Glycosyl-phosphatidylinositol anchored membrane enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Different distributions of human bone alkaline phosphatase isoforms in serum and bone tissue extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Quantitation of soluble and skeletal alkaline phosphatase, and insoluble alkaline phosphatase anchor-hydrolase activities in human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Effect of chronic renal failure on bone turnover and bone alkaline phosphatase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum osteocalcin and bone and liver alkaline phosphatase isoforms in healthy children and adolescents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Circulating and tissue-derived isoforms of bone alkaline phosphatase in Paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

The novel bone alkaline phosphatase B1x isoform in children with kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Clinical significance of bone alkaline phosphatase isoforms, including the novel B1x isoform, in mild to moderate chronic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Bone alkaline phosphatase isoforms in hemodialysis patients with low versus non-low bone turnover: a diagnostic test study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Induction of bone-type alkaline phosphatase in human vascular smooth muscle cells: roles of tumor necrosis factor-alpha and oncostatin M derived from macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Calcifying human aortic smooth muscle cells express different bone alkaline phosphatase isoforms, including the novel B1x isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

21 January 2018

Odontoblast physiology

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Biomineralization and matrix vesicles in biology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Annexin-mediated matrix vesicle calcification in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

The role of phosphatases in the initiation of skeletal mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Mechanism of calcification: inhibitory role of pyrophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

The Possible Significance of Hexosephosphoric Esters in Ossification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Vascular calcification is dependent on plasma levels of pyrophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Peritoneal dialysis per se is a risk factor for sclerostin-associated adynamic bone disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

FGF23 Regulates Bone Mineralization in a 1,25(OH)2 D3 and Klotho-Independent Manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Arterial calcification in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

NT5E mutations and arterial calcifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Transgenic Overexpression of Tissue-Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Pathophysiology of Vascular Calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Phosphorus overload and PTH induce aortic expression of Runx2 in experimental uraemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Effect of bone mineral guideline target achievement on mortality in incident dialysis patients: an analysis of the United Kingdom Renal Registry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Bone alkaline phosphatase in CKD-mineral bone disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum alkaline phosphatase levels associate with elevated serum C-reactive protein in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Alkaline phosphatase and percentage body fat predict circulating C-reactive protein in premenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association between C-reactive protein and biomarkers of bone and mineral metabolism in chronic hemodialysis patients: a cross-sectional study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum Alkaline Phosphatase and Risk of Incident Cardiovascular Disease: Interrelationship with High Sensitivity C-Reactive Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Associations of serum skeletal alkaline phosphatase with elevated C-reactive protein and mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Effects of C-reactive protein on bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Impact of ectoenzymes on p2 and p1 receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

CD39 and CD73 in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal alkaline phosphatase: a summary of its role in clinical disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

A novel hypothesis for an alkaline phosphatase 'rescue' mechanism in the hepatic acute phase immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

The P2Y2 nucleotide receptor is an inhibitor of vascular calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal alkaline phosphatase: novel functions and protective effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Soluble CD14 levels, interleukin 6, and mortality among prevalent hemodialysis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD-Related Systemic Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Resistant starch alters gut microbiome and metabolomic profiles concurrent with amelioration of chronic kidney disease in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal alkaline phosphatase preserves the normal homeostasis of gut microbiota.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal alkaline phosphatase prevents antibiotic-induced susceptibility to enteric pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal alkaline phosphatase prevents metabolic syndrome in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

A High Level of Intestinal Alkaline Phosphatase Is Protective Against Type 2 Diabetes Mellitus Irrespective of Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Cellular localization of endothelial alkaline phosphatase reaction product and enzyme protein in the myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Tissue Non-specific Alkaline Phosphatase (TNAP) in Vessels of the Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Vascular Cell Senescence Contributes to Blood-Brain Barrier Breakdown.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

An alkaline phosphatase transport mechanism in the pathogenesis of Alzheimer's disease and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum alkaline phosphatase negatively affects endothelium-dependent vasodilation in naïve hypertensive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Oxidative stress modulates osteoblastic differentiation of vascular and bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

p-Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Eotaxin Augments Calcification in Vascular Smooth Muscle Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Oxidative Stress as Estimated by Gamma-Glutamyl Transferase Levels Amplifies the Alkaline Phosphatase-Dependent Risk for Mortality in ESKD Patients on Dialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Associations between renal hyperfiltration and serum alkaline phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Renal glomerular and tubular injury after gastric bypass in obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Electron-microscopic demonstration of alkaline-phosphatase activity in the juxtaglomerular apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Hypophosphatasia - aetiology, nosology, pathogenesis, diagnosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Liver enzymes and risk of cardiovascular disease in the general population: a meta-analysis of prospective cohort studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association of alkaline phosphatase with acute myocardial infarction in a population with high prevalence of hypovitaminosis D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum alkaline phosphatase is a predictor of mortality, myocardial infarction, or stent thrombosis after implantation of coronary drug-eluting stent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association of serum alkaline phosphatase with coronary artery calcification in maintenance hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Arterial calcifications and bone histomorphometry in end-stage renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association of changes in bone remodeling and coronary calcification in hemodialysis patients: a prospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Adynamic bone disease: from bone to vessels in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Reduced plasma pyrophosphate levels in hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Treatment with pyrophosphate inhibits uremic vascular calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Relation between alkaline phosphatase, serum phosphate, and all-cause or cardiovascular mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum alkaline phosphatase predicts mortality among maintenance hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum alkaline phosphatase and mortality in African Americans with chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Outcome predictability of serum alkaline phosphatase in men with pre-dialysis CKD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Mineral and bone disorders and survival in hemodialysis patients with and without polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Comparative mortality-predictability using alkaline phosphatase and parathyroid hormone in patients on peritoneal dialysis and hemodialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Alkaline phosphatase and mortality in patients on peritoneal dialysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Impact of age on survival predictability of bone turnover markers in hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Prognostic importance of serum alkaline phosphatase in CKD stages 3-4 in a clinical population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association of serum alkaline phosphatase with mortality in non-selected European patients with CKD5D: an observational, three-centre survival analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Changes in Markers of Mineral and Bone Disorders and Mortality in Incident Hemodialysis Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association of pre-kidney transplant markers of mineral and bone disorder with post-transplant outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Markers of the hepatic component of the metabolic syndrome as predictors of mortality in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Combined alkaline phosphatase and phosphorus levels as a predictor of mortality in maintenance hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Effect Modifying Role of Serum Calcium on Mortality-Predictability of PTH and Alkaline Phosphatase in Hemodialysis Patients: An Investigation Using Data from the Taiwan Renal Registry Data System from 2005 to 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Serum Alkaline Phosphatase Levels are Not Associated with Increased Death Risk in Prevalent Hemodialysis Patients: 5-Year Experience in a Single Hemodialysis Center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Bone-specific alkaline phosphatase concentrations are less variable than those of parathyroid hormone in stable hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Variability of parathyroid hormone and other markers of bone mineral metabolism in patients receiving hemodialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

PTH--a particularly tricky hormone: why measure it at all in kidney patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Does PTH offer additive value to ALP measurement in assessing CKD-MBD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Residues determining the binding specificity of uncompetitive inhibitors to tissue-nonspecific alkaline phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Identification and characterization of novel tissue-nonspecific alkaline phosphatase inhibitors with diverse modes of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Inhibitors of tissue-nonspecific alkaline phosphatase: design, synthesis, kinetics, biomineralization and cellular tests.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase: effects on cell toxicity and osteoblast-induced mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Enzyme-replacement therapy in life-threatening hypophosphatasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Asfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Anti-inflammatory effects of alkaline phosphatase in coronary artery bypass surgery with cardiopulmonary bypass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Curcumin and chronic kidney disease (CKD): major mode of action through stimulating endogenous intestinal alkaline phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Oral supplementation with non-absorbable antibiotics or curcumin attenuates western diet-induced atherosclerosis and glucose intolerance in LDLR-/- mice--role of intestinal permeability and macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Alkaline Phosphatase, Serum Phosphate, and Incident Cardiovascular Disease and Total Mortality in Older Men

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Induction of glomerular alkaline phosphatase after challenge with lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Effect of Magnesium Deficiency on Plasma Alkaline Phosphatase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Association between plasma alkaline phosphatase and C-reactive protein in Hong Kong Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Bone Alkaline Phosphatase and Mortality in Dialysis Patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Mammalian Alkaline Phosphatases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Different responses of bone alkaline phosphatase isoforms during recombinant insulin-like growth factor-I (IGF-I) and during growth hormone therapy in adults with growth hormone deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Determination of alkaline phosphatase isoenzymes in serum by high-performance liquid chromatography with post-column reaction detection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Monoclonal antibodies against tissue-nonspecific alkaline phosphatase. Report of the ISOBM TD9 workshop

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

How glycosylphosphatidylinositol-anchored membrane proteins are made

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Methodological aspects on separation and reaction conditions of bone and liver alkaline phosphatase isoform analysis by high-performance liquid chromatography

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Isoforms of bone alkaline phosphatase: characterization and origin in human trabecular and cortical bone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Mechanisms of calcification: role of collagen, polyphosphates, and phosphatase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Bone Alkaline Phosphatase and Tartrate-Resistant Acid Phosphatase: Potential Co-regulators of Bone Mineralization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Phosphate, pyrophosphate, and vascular calcification: a question of balance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Bone markers predict cardiovascular events in chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

TNF-α stimulates alkaline phosphatase and mineralization through PPARγ inhibition in human osteoblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

IL-1beta induces alkaline phosphatase in human phagocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Lipopolysaccharide administration increases acid and alkaline phosphatase reactivity in the cardiac muscle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Aberrant Circulating Levels of Purinergic Signaling Markers Are Associated With Several Key Aspects of Peripheral Atherosclerosis and Thrombosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Intestinal alkaline phosphatase in patients with chronic renal failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Letter: Increased intestinal alkaline phosphatase in serum of patients on maintenance haemodialysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Increased serum concentrations of intestinal alkaline phosphatase in peritoneal dialysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Clostridium difficile-Associated diarrhoea in uremic patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Metabolic syndrome and chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Alkaline phosphatase is independently associated with renal function in normoalbuminuric type 1 diabetic patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Change in alkaline phosphatase isoenzyme pattern in urine as possible marker for renal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Presence of alkaline phosphatase and γ-glutamyl transpeptidase on the parietal layer of Bowman's capsule

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Evidence for abnormal calcium homeostasis in patients with adynamic bone disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Age-independent association between arterial and bone remodeling in mild-to-moderate chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

High alkaline phosphatase levels in hemodialysis patients are associated with higher risk of hospitalization and death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

A higher serum alkaline phosphatase is associated with the incidence of hip fracture and mortality among patients receiving hemodialysis in Japan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Hypocalcemia, morbidity, and mortality in end-stage renal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Predicting first-year mortality in incident dialysis patients with end-stage renal disease - the UREA5 study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Prognostic significance of pre-end-stage renal disease serum alkaline phosphatase for post-end-stage renal disease mortality in late-stage chronic kidney disease patients transitioning to dialysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

Higher serum bone alkaline phosphatase as a predictor of mortality in male hemodialysis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2017.60

HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis

31 March 2020

1 reference

12 December 2020

Multiple forms of alkaline phosphatase in plasma of hemodialysis patients

1 reference

12 December 2020

Serum alkaline phosphatase and mortality in hemodialysis patients.

1 reference

12 December 2020

Structure of the human liver/bone/kidney alkaline phosphatase gene

1 reference

12 December 2020

Criteria for establishing a standardized method for determining alkaline phosphatase activity in human serum

1 reference

12 December 2020

Differences of bone alkaline phosphatase isoforms in metastatic bone disease and discrepant effects of clodronate on different skeletal sites indicated by the location of pain.

1 reference

12 December 2020

KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD).

1 reference

12 December 2020

Transferability studies for the AACC reference method and the IFCC method for measurement of alkaline phosphatase activity

1 reference

12 December 2020

Relationship between alkaline phosphatase and all-cause mortality in peritoneal dialysis patients

1 reference

12 December 2020

The source and clinical significance of serum alkaline phosphatases in patients treated by chronic dialysis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2017.60

1 reference

11 June 2017

1 reference

PubMed ID

28502983