Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement (Q30306561)

16 June 2017

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title

Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement (English)

1 reference

16 June 2017

Parsons JT

1

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16 June 2017

Martin KH

2

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16 June 2017

Slack JK

3

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16 June 2017

Taylor JM

4

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16 June 2017

Weed SA

5

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16 June 2017

language of work or name

English

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publication date

1 November 2000

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16 June 2017

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16 June 2017

19

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16 June 2017

49

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16 June 2017

5606-5613

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Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

16 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

1 reference

7 January 2021

Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Crosstalk between Rac and Rho.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Focal adhesions, contractility, and signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Assembly of focal adhesions: progress, paradigms, and portents

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The N-termini of FAK and JAKs contain divergent band 4.1 domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Rho GTPases and the actin cytoskeleton

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Association of focal adhesion kinase with Grb7 and its role in cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Cell migration--movin' on.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

A role for p21-activated kinase in endothelial cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Regulation of cell motility by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Src family kinases are required for integrin but not PDGFR signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Cell migration: a physically integrated molecular process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The Arp2/3 complex: a multifunctional actin organizer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrin signalling: a new Cas(t) of characters enters the stage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

DFak56 is a novel Drosophila melanogaster focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Interplay between Rac and Rho in the control of substrate contact dynamics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrins: emerging paradigms of signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Characterization of graf, the GTPase-activating protein for rho associated with focal adhesion kinase. Phosphorylation and possible regulation by mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Diphtheria toxin-mediated ablation of parietal cells in the stomach of transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203877

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203877

1 reference

Dimensions Publication ID

16 June 2017

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1 reference