Acidic priming enhances metastatic potential of cancer cells (Q30317522)

17 June 2017

title

Acidic priming enhances metastatic potential of cancer cells (English)

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17 June 2017

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6

Michael Gekle

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17 June 2017

Anne Riemann

1

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17 June 2017

Bettina Schneider

2

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17 June 2017

Daniel Gündel

3

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17 June 2017

Christian Stock

4

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17 June 2017

Oliver Thews

5

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17 June 2017

publication date

16 February 2014

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17 June 2017

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17 June 2017

volume

466

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17 June 2017

issue

11

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17 June 2017

page(s)

2127-2138

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Acidic pH stimulates the production of the angiogenic CXC chemokine, CXCL8 (interleukin-8), in human adult mesenchymal stem cells via the extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and NF-kappaB pathways

17 June 2017

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Heme oxygenase-1 does not mediate the effects of extracellular acidosis on vascular smooth muscle cell proliferation, migration, and susceptibility to apoptosis

21 January 2018

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Regulation of cancer cell metabolism

21 January 2018

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Inhibition of tumor cell migration and metastasis by the proton-sensing GPR4 receptor

21 January 2018

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Acidic stress facilitates tyrosine phosphorylation of HLJ1 to associate with actin cytoskeleton in lung cancer cells

21 January 2018

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An acidic extracellular pH induces Src kinase-dependent loss of beta-catenin from the adherens junction

21 January 2018

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Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

21 January 2018

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Src kinase inhibitors: promising cancer therapeutics?

21 January 2018

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Acidosis inhibits endothelial cell apoptosis and function and induces basic fibroblast growth factor and vascular endothelial growth factor expression.

21 January 2018

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H2O2-treated actin: assembly and polymer interactions with cross-linking proteins

21 January 2018

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MAP kinase signalling pathways in cancer

21 January 2018

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Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes

21 January 2018

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The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 January 2018

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Acid-mediated tumor invasion: a multidisciplinary study

21 January 2018

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Rapid activation of Na+/H+ exchange by aldosterone in renal epithelial cells requires Ca2+ and stimulation of a plasma membrane proton conductance

21 January 2018

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NHE3 serves as a molecular tool for cAMP-mediated regulation of receptor-mediated endocytosis

21 January 2018

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Characterization of two MDCK-cell subtypes as a model system to study principal cell and intercalated cell properties

21 January 2018

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Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles

21 January 2018

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MAP kinases and cell migration

21 January 2018

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Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling.

21 January 2018

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Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma

21 January 2018

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Reactive oxygen species and tumor metastasis

21 January 2018

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Nephrotoxicity of platinum complexes is related to basolateral organic cation transport

21 January 2018

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Intracellular pH gradients in migrating cells

21 January 2018

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Acidic pH enhances the invasive behavior of human melanoma cells

21 January 2018

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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

21 January 2018

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Acid treatment of melanoma cells selects for invasive phenotypes

21 January 2018

1 reference

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Calcium channels and pumps in cancer: changes and consequences

21 January 2018

1 reference

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Invasive potential induced under long-term oxidative stress in mammary epithelial cells

21 January 2018

1 reference

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Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism

21 January 2018

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Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress

21 January 2018

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Acidic environment leads to ROS-induced MAPK signaling in cancer cells

21 January 2018

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Bicarbonate increases tumor pH and inhibits spontaneous metastases

21 January 2018

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Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells

21 January 2018

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How cancer metabolism is tuned for proliferation and vulnerable to disruption

21 January 2018

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Role of ion channels and transporters in cell migration

21 January 2018

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Functional role of Na+-HCO3- cotransport in migration of transformed renal epithelial cells.

21 January 2018

1 reference

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Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange

21 January 2018

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Protons make tumor cells move like clockwork

21 January 2018

1 reference

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Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs

21 January 2018

1 reference

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Impact of reactive oxygen species on the expression of adhesion molecules in vivo

21 January 2018

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Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

21 January 2018

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NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration

21 January 2018

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Redox regulation of cancer cell migration and invasion

21 January 2018

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Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells

21 January 2018

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Guidelines for the welfare and use of animals in cancer research

21 January 2018

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Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

21 January 2018

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Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis

21 January 2018

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Extracellular acidosis accelerates bone resorption by enhancing osteoclast survival, adhesion, and migration

21 January 2018

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12 December 2020

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

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12 December 2020

Vacuolar-type H+-ATPase-mediated acidosis promotes in vitro osteoclastogenesis via modulation of cell migration

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12 December 2020

Use of fluorescent dye BCECF to measure intracellular pH in cortical collecting tubule

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12 December 2020

Thetert-Butyl Hydroperoxide-Induced Oxidation of Actin Cys-374 Is Coupled with Structural Changes in Distant Regions of the Protein†

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12 December 2020

Inhibitory effect of tumor cell-derived lactic acid on human T cells

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12 December 2020

Clinical significance of Src expression and activity in human neoplasia

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12 December 2020

Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice

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12 December 2020

Acidic pH inhibits non-MHC-restricted killer cell functions

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12 December 2020

Imaging pH and metastasis

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12 December 2020

10.1007/S00424-014-1458-6

Identifiers

DOI

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Dimensions Publication ID

17 June 2017

1008297480

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Fatcat ID

release_xms3nildnjfjjj5l7a2tnqdmny

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Fatcat

https://api.fatcat.wiki/v0/release/xms3nildnjfjjj5l7a2tnqdmny

24 November 2022

mapped directly with Wikidata item

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