A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice. (Q30361531)

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English	A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice.	scientific article

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5 April 2020

A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice (English)

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5 April 2020

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5 April 2020

Jaclyn N Highland

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5 April 2020

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Mackenzie E Nelson

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5 April 2020

Samuel R Krimmel

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5 April 2020

Polymnia Georgiou

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5 April 2020

Todd D Gould

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5 April 2020

Scott M Thompson

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1 January 2017

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5 April 2020

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5 April 2020

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5 April 2020

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1 reference

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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.

1 reference

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The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition.

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Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors

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Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats

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Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants

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Chronic stress induces a selective decrease in AMPA receptor-mediated synaptic excitation at hippocampal temporoammonic-CA1 synapses

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The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity

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Activation of mammalian target of rapamycin and synaptogenesis: role in the actions of rapid-acting antidepressants

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Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression

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Ketamine use: a review

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NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

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The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents.

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NMDA receptor-dependent switching between different gamma rhythm-generating microcircuits in entorhinal cortex.

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RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors

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10.1523/ENEURO.0285-16.2017

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