RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors (Q34860798)

4 August 2017

RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors (English)

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4 August 2017

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Theresa M Ballard

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4 August 2017

Frédéric Knoflach

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4 August 2017

Eric Prinssen

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4 August 2017

Edilio Borroni

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4 August 2017

Jeffrey A Vivian

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Jennifer Basile

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4 August 2017

Rodolfo Gasser

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4 August 2017

Jean-Luc Moreau

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4 August 2017

Joseph G Wettstein

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4 August 2017

Bernd Buettelmann

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4 August 2017

Henner Knust

11

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Andrew W Thomas

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4 August 2017

Gerhard Trube

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Maria-Clemencia Hernandez

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4 August 2017

21 October 2008

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202

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1-3

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207-223

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https://scigraph.springernature.com/pub.10.1007/s00213-008-1357-7

4 August 2017

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cites work

The affinities, potencies and efficacies of some benzodiazepine-receptor agonists, antagonists and inverse-agonists at rat hippocampal GABAA-receptors

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Crossref

https://api.crossref.org/works/10.1007%2FS00213-008-1357-7

Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00213-008-1357-7

Donepezil reverses a mnemonic deficit produced by scopolamine but not by perforant path lesion or transient cerebral ischaemia

21 January 2018

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12 December 2020

Developmental and genetic audiogenic seizure models: behavior and biological substrates

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12 December 2020

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

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12 December 2020

GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls

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12 December 2020

GABA(A) receptor diversity and pharmacology

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12 December 2020

The proconvulsant effects of the GABAA alpha5 subtype-selective compound RY-080 may not be alpha5-mediated.

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12 December 2020

Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques.

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12 December 2020

GABA(A) receptor subtype selective cognition enhancers

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12 December 2020

PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats

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12 December 2020

Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus?

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12 December 2020

Bidirectional effects of beta-carbolines and benzodiazepines on cognitive processes.

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12 December 2020

Visualization of alpha5 subunit of GABAA/benzodiazepine receptor by 11C Ro15-4513 using positron emission tomography

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12 December 2020

Molecular and neuronal substrate for the selective attenuation of anxiety.

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12 December 2020

Developments of a water-maze procedure for studying spatial learning in the rat

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12 December 2020

Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function.

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12 December 2020

Blockade of alcohol's amnestic activity in humans by an alpha5 subtype benzodiazepine receptor inverse agonist

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Successful performance by monkeys with lesions of the hippocampal formation on AB and object retrieval, two tasks that mark developmental changes in human infants

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Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

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Synthesis and pharmacological properties of novel 8-substituted imidazobenzodiazepines: high-affinity, selective probes for alpha 5-containing GABAA receptors.

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Pharmacology of the benzodiazepine receptor

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12 December 2020

Severe anxiety induced by FG 7142, a beta-carboline ligand for benzodiazepine receptors.

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12 December 2020

GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits

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12 December 2020

α5GABAA Receptors Regulate the Intrinsic Excitability of Mouse Hippocampal Pyramidal Neurons

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12 December 2020

Density and pharmacology of alpha5 subunit-containing GABA(A) receptors are preserved in hippocampus of Alzheimer's disease patients.

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12 December 2020

Contrasting effects of excitotoxic lesions of the prefrontal cortex on the behavioural response to D-amphetamine and presynaptic and postsynaptic measures of striatal dopamine function in monkeys

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12 December 2020

The effects of a benzodiazepine receptor antagonist beta-carboline ZK-93426 on scopolamine-induced impairment on attention, memory and psychomotor skills

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12 December 2020

Role of GABA abnormalities in the inferior colliculus pathophysiology - audiogenic seizures

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12 December 2020

Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography

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12 December 2020

Selective, orally active gamma-aminobutyric acidA alpha5 receptor inverse agonists as cognition enhancers.

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12 December 2020

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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12 December 2020

A novel benzodiazepine inverse agonist, S-8510, as a cognitive enhancer.

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12 December 2020

Effects of ibotenate hippocampal and extrahippocampal destruction on delayed-match and -nonmatch-to-sample behavior in rats.

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Social approach-avoidance behavior of a high-anxiety strain of rats: effects of benzodiazepine receptor ligands

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12 December 2020

Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety

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12 December 2020

Chlordiazepoxide, an anxiolytic benzodiazepine, impairs place navigation in rats.

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12 December 2020

An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

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12 December 2020

Removal of the hippocampus and transection of the fornix produce comparable deficits on delayed non-matching to position by rats.

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12 December 2020

Differential pharmacological effects of benzodiazepine receptor inverse agonists

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12 December 2020

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

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12 December 2020

The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison

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12 December 2020

An inverse agonist selective for alpha5 subunit-containing GABAA receptors improves encoding and recall but not consolidation in the Morris water maze.

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12 December 2020

[3H]L-655,708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit

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12 December 2020

Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human [...]

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12 December 2020

Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent.

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12 December 2020

Modulation of long-term potentiation in CA1 region of mouse hippocampal brain slices by GABAA receptor benzodiazepine site ligands.

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12 December 2020

Donepezil for dementia due to Alzheimer's disease

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12 December 2020

Memantine for dementia

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12 December 2020

Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.

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12 December 2020

L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for alpha5-containing GABAA receptors.

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12 December 2020

Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks

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12 December 2020

Benzodiazepines block long-term potentiation in slices of hippocampus and piriform cortex

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12 December 2020

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

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12 December 2020

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

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12 December 2020

10.1007/S00213-008-1357-7

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Dimensions Publication ID

4 August 2017

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