Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations (Q30389638)

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12 March 2020

title

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations (English)

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12 March 2020

5

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Lingjiao Zhang

7

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12 March 2020

Douglas A Marchuk

16

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ORCID Public Data File 2021

author name string

Robert Shenkar

1

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Changbin Shi

2

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Tania Rebeiz

3

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Rebecca A Stockton

4

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Abdul Ghani Mikati

6

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Cecilia Austin

8

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12 March 2020

Amy L Akers

9

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Carol J Gallione

10

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Autumn Rorrer

11

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Murat Gunel

12

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Wang Min

13

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Connie Lee

15

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Issam A Awad

17

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Jorge Marcondes De Souza

14

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12 March 2020

language of work or name

English

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publication date

14 August 2014

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12 March 2020

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12 March 2020

volume

17

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issue

3

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12 March 2020

page(s)

188-196

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Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration

12 March 2020

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A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils

20 June 2018

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CCM3 Mutations Are Associated with Early-Onset Cerebral Hemorrhage and Multiple Meningiomas

20 June 2018

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Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

20 June 2018

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Genetic and cellular basis of cerebral cavernous malformations: implications for clinical management

20 June 2018

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Untreated clinical course of cerebral cavernous malformations: a prospective, population-based cohort study

20 June 2018

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Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease

20 June 2018

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The natural history of intracranial cavernous malformations

20 June 2018

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CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization

20 June 2018

1 reference

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The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ.

20 June 2018

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A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.

20 June 2018

1 reference

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Evaluating strategies for the treatment of cerebral cavernous malformations

20 June 2018

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Pleiotropic effects of statins. - Basic research and clinical perspectives -.

20 June 2018

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CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

20 June 2018

1 reference

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Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

20 June 2018

1 reference

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Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype

20 June 2018

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Immune response in human cerebral cavernous malformations

20 June 2018

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The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

20 June 2018

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Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis

20 June 2018

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Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models

20 June 2018

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Hemorrhage from cavernous malformations of the brain: definition and reporting standards. Angioma Alliance Scientific Advisory Board

20 June 2018

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Low frequency of PDCD10 mutations in a panel of CCM3 probands: potential for a fourth CCM locus

20 June 2018

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20 June 2018

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Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations

20 June 2018

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20 June 2018

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EndMT contributes to the onset and progression of cerebral cavernous malformations

20 June 2018

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Cavernous malformations and hemorrhage risk

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21 January 2018

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Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.

21 January 2018

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Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease

21 January 2018

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21 January 2018

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Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion.

21 January 2018

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Frequency and phenotypes of cutaneous vascular malformations in a consecutive series of 417 patients with familial cerebral cavernous malformations.

21 January 2018

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A method for measuring Rho kinase activity in tissues and cells

21 January 2018

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25122144

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Spectrum of genotype and clinical manifestations in cerebral cavernous malformations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25122144

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/GIM.2014.97

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25122144%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Microsoft Academic ID

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25122144%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

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