EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer. (Q30405442)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379240%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer (English)

1 reference

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4 March 2020

1 reference

1 reference

6

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Cristian Rodriguez-Aguayo

4 March 2020

9

1 reference

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4 March 2020

11

Anil K Sood

1 reference

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4 March 2020

author name string

Amber Bradley

1

1 reference

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4 March 2020

Hui Zheng

2

1 reference

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4 March 2020

Angela Ziebarth

3

1 reference

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4 March 2020

Wayne Sakati

4

1 reference

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4 March 2020

Melissa Branham-O'Connor

5

1 reference

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4 March 2020

Yuying Liu

7

1 reference

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4 March 2020

Emily Kistner-Griffin

8

1 reference

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4 March 2020

Gabriel Lopez-Berestein

10

1 reference

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4 March 2020

Charles N Landen

12

1 reference

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4 March 2020

Scott T Eblen

13

1 reference

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4 March 2020

language of work or name

English

0 references

publication date

30 December 2013

1 reference

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4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379240%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

35

1 reference

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4 March 2020

issue

5

1 reference

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4 March 2020

page(s)

1100-1109

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Secreted frizzled-related protein 4 expression is positively associated with responsiveness to cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers

4 March 2020

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20 June 2018

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Molecular mechanisms of cisplatin resistance

20 June 2018

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Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis

20 June 2018

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MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance

20 June 2018

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Role of Bcl-2 family proteins and caspases in the regulation of apoptosis.

20 June 2018

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Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

20 June 2018

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The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin

20 June 2018

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Caspase-3 triggers a TPCK-sensitive protease pathway leading to degradation of the BH3-only protein puma

20 June 2018

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Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells.

20 June 2018

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Bcl-XL and MCL-1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis.

20 June 2018

1 reference

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A composite intronic element directs dynamic binding of the progesterone receptor and GATA-2.

20 June 2018

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Targeting aurora kinase with MK-0457 inhibits ovarian cancer growth.

20 June 2018

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The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro

20 June 2018

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Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth

20 June 2018

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Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

20 June 2018

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Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer

20 June 2018

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EDD mediates DNA damage-induced activation of CHK2

20 June 2018

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Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.

20 June 2018

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EphA2 as a target for ovarian cancer therapy

20 June 2018

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Long-term treatment with novel glycogen synthase kinase-3 inhibitor improves glucose homeostasis in ob/ob mice: molecular characterization in liver and muscle

20 June 2018

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20 June 2018

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An evaluation of cytotoxicity of the taxane and platinum agents combination treatment in a panel of human ovarian carcinoma cell lines

20 June 2018

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Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors

20 June 2018

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20 June 2018

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Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

20 June 2018

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20 June 2018

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EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer

20 June 2018

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Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs

20 June 2018

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EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response

20 June 2018

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Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter

20 June 2018

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20 June 2018

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Molecular targets of lithium action

20 June 2018

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Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2.

20 June 2018

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Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs

20 June 2018

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mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

20 June 2018

1 reference

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Comparative genomic hybridization analysis of chromosomal changes occurring during development of acquired resistance to cisplatin in human ovarian carcinoma cells

20 June 2018

1 reference

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A molecular mechanism for the effect of lithium on development

20 June 2018

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The E3 ubiquitin ligase EDD regulates S-phase and G(2)/M DNA damage checkpoints.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT489

First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT489

Increased MCL-1 expression is associated with poor prognosis in ovarian carcinomas

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT489

Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers.

21 January 2018

1 reference

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Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24379240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of phosphorylation sites on the E3 ubiquitin ligase UBR5/EDD

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24379240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Liposomal siRNA for ovarian cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24379240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/CARCIN/BGT489

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379240%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379240%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

24379240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24379240%20AND%20SRC:MED&resulttype=core&format=json