Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. (Q30408186)

4 October 2017

Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. (English)

1 reference

4 October 2017

0 references

1 reference

7

1 reference

Oksana Kaidanovich-Beilin

4 October 2017

object named as

Oksana Kaidanovich-Beilin

2

0 references

author name string

Tatiana V Lipina

1

1 reference

4 October 2017

Satish Patel

3

1 reference

4 October 2017

Min Wang

4

1 reference

4 October 2017

Steven J Clapcote

5

1 reference

4 October 2017

Fang Liu

6

1 reference

4 October 2017

John C Roder

8

1 reference

4 October 2017

1 March 2011

1 reference

4 October 2017

1 reference

4 October 2017

65

1 reference

4 October 2017

234-248

1 reference

4 October 2017

3

1 reference

describes a project that uses

4 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4485461/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

When pathways collide: collaboration and connivance among signalling proteins in development.

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Temporal lobe grey matter volume in schizophrenia is associated with a genetic polymorphism influencing glycogen synthase kinase 3-β activity

20 June 2018

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20 June 2018

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Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

20 June 2018

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Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action

20 June 2018

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Understanding the role of DISC1 in psychiatric disease and during normal development

20 June 2018

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DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

20 June 2018

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Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.

20 June 2018

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Early effects of mood stabilizers on the Akt/GSK-3beta signaling pathway and on cell survival and proliferation

20 June 2018

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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

20 June 2018

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Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain

20 June 2018

1 reference

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Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses

20 June 2018

1 reference

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Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: role of GSK-3beta in adult brain

20 June 2018

1 reference

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Akt/GSK3 signaling in the action of psychotropic drugs

20 June 2018

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Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action

20 June 2018

1 reference

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A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

20 June 2018

1 reference

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Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

20 June 2018

1 reference

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Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

20 June 2018

1 reference

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The role of glycogen synthase kinase-3beta in schizophrenia

20 June 2018

1 reference

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Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

20 June 2018

1 reference

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The DISC locus in psychiatric illness

20 June 2018

1 reference

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Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.

20 June 2018

1 reference

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Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

20 June 2018

1 reference

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Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles

20 June 2018

1 reference

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cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling

20 June 2018

1 reference

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LTP inhibits LTD in the hippocampus via regulation of GSK3beta

20 June 2018

1 reference

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Schizophrenia as a GSK-3 dysregulation disorder

20 June 2018

1 reference

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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

20 June 2018

1 reference

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Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions

20 June 2018

1 reference

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Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease

20 June 2018

1 reference

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Glycogen synthase kinase-3--an overview of an over-achieving protein kinase

20 June 2018

1 reference

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Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.

20 June 2018

1 reference

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Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

20 June 2018

1 reference

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Phosphodiesterase inhibitors.

20 June 2018

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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

20 June 2018

1 reference

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Keynote review: phosphodiesterase-4 as a therapeutic target

20 June 2018

1 reference

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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

20 June 2018

1 reference

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Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia

20 June 2018

1 reference

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Pharmacological inhibitors of glycogen synthase kinase 3.

20 June 2018

1 reference

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Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Phenotype of schizophrenia: a review and formulation

20 June 2018

1 reference

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Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

20 June 2018

1 reference

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Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4).

20 June 2018

1 reference

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Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Animal behavior models of the mechanisms underlying antipsychotic atypicality

20 June 2018

1 reference

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Diverse psychotomimetics act through a common signaling pathway

20 June 2018

1 reference

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GSK3 takes centre stage more than 20 years after its discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

20 June 2018

1 reference

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Disruption of two novel genes by a translocation co-segregating with schizophrenia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Haloperidol- and clozapine-induced enhancement of latent inhibition with extended conditioning: implications for the mechanism of action of neuroleptic drugs.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

A molecular mechanism for the effect of lithium on development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Effects of antipsychotic drugs on latent inhibition: sensitivity and specificity of an animal behavioral model of clinical drug action.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Regulation and functions of the glycogen synthase kinase-3 subfamily

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Molecular cloning and expression of glycogen synthase kinase-3/factor A

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Alzheimer's disease: a cell biological perspective

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Information-processing deficits and thought disorder in schizophrenia.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FSYN.20839

Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FSYN.20839

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FSYN.20839

A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Association study of GSK3 gene polymorphisms with schizophrenia and clozapine response

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Behavioral phenotypes of Disc1 missense mutations in mice.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

The PDE4B gene confers sex-specific protection against schizophrenia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Rolipram attenuates MK-801-induced deficits in latent inhibition

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Neurogranin null mutant mice display performance deficits on spatial learning tasks with anxiety related components

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485461

The pharmacology of latent inhibition as an animal model of schizophrenia

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20687111

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurobiology of schizophrenia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20687111

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/SYN.20839

1 reference

4 October 2017

1 reference

4 October 2017

1 reference