Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1. (Q30411120)

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English	Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 October 2017

Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1. (English)

1 reference

Europe PubMed Central

1 October 2017

Marije Koenders

2

1 reference

Europe PubMed Central

1 October 2017

Charles A. Dinarello

5

object named as

Charles A Dinarello

1 reference

Europe PubMed Central

1 October 2017

4

object named as

Mihai G Netea

1 reference

Europe PubMed Central

1 October 2017

Leo A.B. Joosten

6

object named as

Leo A B Joosten

1 reference

Europe PubMed Central

1 October 2017

1

object named as

Bas Heinhuis

1 reference

Europe PubMed Central

1 October 2017

author name string

Wim B van den Berg

3

1 reference

Europe PubMed Central

1 October 2017

language of work or name

0 references

publication date

27 December 2011

1 reference

Europe PubMed Central

1 October 2017

number of pages

11

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

1 October 2017

287

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Europe PubMed Central

1 October 2017

8

1 reference

Europe PubMed Central

1 October 2017

5733-5743

1 reference

Europe PubMed Central

1 October 2017

Integrin targeted therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Protection from RNA and DNA viruses by IL-32.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Intracellular targets of RGDS peptide in melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

I-TASSER: a unified platform for automated protein structure and function prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Interleukin-32 expression in the pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

The ins and outs of leukocyte integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

IL-32-dependent effects of IL-1beta on endothelial cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Interleukin-32 promotes osteoclast differentiation but not osteoclast activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Endogenous IL-32 controls cytokine and HIV-1 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Increased level of IL-32 during human immunodeficiency virus infection suppresses HIV replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Interleukin-32 induces the differentiation of monocytes into macrophage-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

I-TASSER server for protein 3D structure prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Structural basis for the autoinhibition of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Cellular characterization of a novel focal adhesion kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Structural basis of integrin regulation and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

IL-32, a novel cytokine with a possible role in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

IL-32, a proinflammatory cytokine in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Proteinase 3 is an IL-32 binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Involvement of IL-32 in activation-induced cell death in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Interleukin-32: a cytokine and inducer of TNFalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Therapeutic antagonists and conformational regulation of integrin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

The HMMTOP transmembrane topology prediction server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

RGD peptides induce apoptosis by direct caspase-3 activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

RGD and other recognition sequences for integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

1 reference

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20 June 2018

Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif

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20 June 2018

Identification of a novel gene expressed in activated natural killer cells and T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

20 June 2018

IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Proteinase 3-processed form of the recombinant IL-32 separate domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

RGD peptide-induced cell death of chondrocytes and synovial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Flipping the safety catch of procaspase-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Development of defined media for the serum-free expansion of primary keratinocytes and human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

ERK 1/2- and JNKs-dependent synthesis of interleukins 6 and 8 by fibroblast-like synoviocytes stimulated with protein I/II, a modulin from oral streptococci, requires focal adhesion kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Cross talk between MyD88 and focal adhesion kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Effect of interleukin-32gamma on differentiation of osteoclasts from CD14+ monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

26 November 2018

Detection of expressed IL-32 in human stomach cancer using ELISA and immunostaining.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

26 November 2018

Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

26 November 2018

A large subset of neutrophils expressing membrane proteinase 3 is a risk factor for vasculitis and rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285345

26 November 2018

IL-32 and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade

2 references

https://api.crossref.org/works/10.1074%2FJBC.M111.288290

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct activation of caspases by RGD-peptides may increase drug sensitivity of tumour cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin inhibitors reaching the clinic

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha-induced interleukin-32 is positively regulated via the Syk/protein kinase Cdelta/JNK pathway in rheumatoid synovial fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of IL-32 in human lung cancer is related to the histotype and metastatic phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitronectin--a major cell attachment-promoting protein in fetal bovine serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22203669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.288290

1 reference

Europe PubMed Central

1 October 2017

1 reference

Europe PubMed Central

1 October 2017

1 reference

Europe PubMed Central

1 October 2017

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