Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis (Q30411394)

21 August 2017

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis (English)

1 reference

21 August 2017

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23

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21 August 2017

Yvonne T van der Schouw

25

1 reference

21 August 2017

16

Tom S Price

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Garret A. FitzGerald

26

Garret A FitzGerald

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Daniel I. Swerdlow

Daniel I Swerdlow

14

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Sarah G Buxbaum

Sarah Buxbaum

7

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Matthew B Lanktree

Matthew B Lanktree

4

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Tom Palmer

Tom Palmer

3

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Folkert Asselbergs

Folkert W Asselbergs

32

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Mary Cushman

Mary Cushman

15

0 references

Hakon Hakonarson

19

Hakon Hakonarson

1 reference

21 August 2017

27

Aroon D Hingorani

1 reference

21 August 2017

Ron C Hoogeveen

11

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Susan Redline

21

Susan Redline

1 reference

21 August 2017

Yun R Li

13

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David S Siscovick

22

David S Siscovick

1 reference

21 August 2017

5

Kari E North

1 reference

21 August 2017

24

James G Wilson

1 reference

21 August 2017

31

Eric E Schadt

1 reference

21 August 2017

2

Leslie A Lange

1 reference

21 August 2017

Michael V Holmes

1

1 reference

21 August 2017

Berta Almoguera

6

1 reference

21 August 2017

Hareesh R Chandrupatla

8

1 reference

21 August 2017

Clara C Elbers

9

1 reference

21 August 2017

Yiran Guo

10

1 reference

21 August 2017

Jin Li

12

1 reference

21 August 2017

Sean P Curtis

17

1 reference

21 August 2017

Sanjay R Patel

20

1 reference

21 August 2017

Juan P Casas

28

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21 August 2017

Paul I W de Bakker

29

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21 August 2017

Stephen S Rich

30

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21 August 2017

Alex P Reiner

33

1 reference

21 August 2017

Brendan J Keating

34

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21 August 2017

language of work or name

English

0 references

publication date

23 January 2014

1 reference

American Journal of Human Genetics

21 August 2017

1 reference

21 August 2017

94

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21 August 2017

198-208

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21 August 2017

2

1 reference

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Lifestyle intervention and/or statins for the reduction of C-reactive protein in type 2 diabetes: from the look AHEAD study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Loci influencing blood pressure identified using a cardiovascular gene-centric array

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

The effect of non-differential measurement error on bias, precision and power in Mendelian randomization studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Blood pressure loci identified with a gene-centric array

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Large-scale gene-centric analysis identifies novel variants for coronary artery disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Avoiding bias from weak instruments in Mendelian randomization studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Association between body-mass index and risk of death in more than 1 million Asians

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Using multiple genetic variants as instrumental variables for modifiable risk factors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Body-Mass Index and Mortality among 1.46 Million White Adults

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Chipping away the 'missing heritability': GIANT steps forward in the molecular elucidation of obesity - but still lots to go.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Candidate gene association resource (CARe): design, methods, and proof of concept

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Common variants in HSPB7 and FRMD4B associated with advanced heart failure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Mortality, health outcomes, and body mass index in the overweight range: a science advisory from the American Heart Association

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Measuring inconsistency in meta-analyses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Multi-Ethnic Study of Atherosclerosis: objectives and design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Hypothesis concerning the U-shaped relation between body mass index and mortality

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Impact of body mass index on coronary heart disease risk factors in men and women. The Framingham Offspring Study.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

CARDIA: study design, recruitment, and some characteristics of the examined subjects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

The Cardiovascular Health Study: design and rationale

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

The framingham offspring study. Design and preliminary data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Instrumental Variable Estimation of Causal Risk Ratios and Causal Odds Ratios in Mendelian Randomization Analyses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Cohort Profile: The EPIC-NL study

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928659

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24462370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.AJHG.2013.12.014

1 reference

21 August 2017

1 reference

21 August 2017

1 reference