Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells (Q30414664)

15 August 2017

Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells (English)

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15 August 2017

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2

Alexander Paliege

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15 August 2017

10

Kai-Uwe Eckardt

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15 August 2017

Birguel Kurt

1

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15 August 2017

Carsten Willam

3

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15 August 2017

Ilona Schwarzensteiner

4

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15 August 2017

Kathrin Schucht

5

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15 August 2017

Hanna Neymeyer

6

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15 August 2017

Maria Luisa S Sequeira-Lopez

7

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15 August 2017

Sebastian Bachmann

8

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15 August 2017

R Ariel Gomez

9

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15 August 2017

Armin Kurtz

11

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15 August 2017

7 February 2013

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Journal of the American Society of Nephrology

15 August 2017

1 reference

15 August 2017

24

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15 August 2017

3

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15 August 2017

433-444

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describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3582205/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.

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Development of the renal arterioles

20 June 2018

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Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis

20 June 2018

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Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury

20 June 2018

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Reciprocal expression of connexin 40 and 45 during phenotypical changes in renin-secreting cells

20 June 2018

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Renin-angiotensin system in kidney development: renal tubular dysgenesis

20 June 2018

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The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.

20 June 2018

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Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

20 June 2018

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Nonrenal regulation of EPO synthesis

20 June 2018

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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

20 June 2018

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Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice

20 June 2018

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Epidermal sensing of oxygen is essential for systemic hypoxic response

20 June 2018

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The VHL tumor suppressor and HIF: insights from genetic studies in mice

20 June 2018

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

20 June 2018

1 reference

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Hypoxia-inducible factors in the kidney

20 June 2018

1 reference

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pVHL function is essential for endothelial extracellular matrix deposition.

20 June 2018

1 reference

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Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor

20 June 2018

1 reference

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Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis

20 June 2018

1 reference

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Role of VHL gene mutation in human cancer

20 June 2018

1 reference

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Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice

20 June 2018

1 reference

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Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

20 June 2018

1 reference

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Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened

20 June 2018

1 reference

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A new method for large scale isolation of kidney glomeruli from mice

20 June 2018

1 reference

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Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys

20 June 2018

1 reference

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Oxygen sensors and angiogenesis

20 June 2018

1 reference

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Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

20 June 2018

1 reference

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Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila

20 June 2018

1 reference

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

20 June 2018

1 reference

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Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

20 June 2018

1 reference

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Angiotensinogen-deficient mice with hypotension

20 June 2018

1 reference

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The distribution of renin in the different segments of the renal arterial tree: immunocytochemical investigation in the mouse kidney

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Tissue and gene specificity of mouse renin expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Is renin substrate an erythropoietin precursor?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat.

20 June 2018

1 reference

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Extra-renal transcription of the renin genes in multiple tissues of mice and rats

20 June 2018

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

20 June 2018

1 reference

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Metaplasia of smooth muscle cells into juxtaglomerular cells in the juxtaglomerular apparatus, arteries, and arterioles of the ischemic (endocrine) kidney. An ultrastructural-cytochemical and autoradiographic study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Developmental renin expression in mice with a defective renin-angiotensin system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Effect of apocynin treatment on renal expression of COX-2, NOS1, and renin in Wistar-Kyoto and spontaneously hypertensive rats

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Reporter gene recombination in juxtaglomerular granular and collecting duct cells by human renin promoter-Cre recombinase transgene.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Preserved macula densa-dependent renin secretion in A1 adenosine receptor knockout mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Fetal toxic effects and angiotensin-II-receptor antagonists

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3582205

Expression of a renin/GFP transgene in mouse embryonic, extra-embryonic, and adult tissues

26 November 2018

1 reference

12 December 2020

Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization

1 reference

12 December 2020

The distribution of renin-containing cells in kidneys with renal artery stenosis--an immunocytochemical study

1 reference

12 December 2020

Co-localization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin

1 reference

12 December 2020

Angiotensin-converting enzyme inhibitor fetopathy

1 reference

12 December 2020

Identification of the renal erythropoietin-producing cells using transgenic mice

1 reference

12 December 2020

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice

1 reference

12 December 2020

Development of renin expression in the mouse kidney

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2012080791

1 reference

15 August 2017

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15 August 2017

PubMed publication ID

23393316

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