Focused ultrasound-induced blood-brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study (Q30416228)

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English	Focused ultrasound-induced blood-brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study	scientific article

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scholarly article

1 reference

Europe PubMed Central

16 October 2017

Focused ultrasound-induced blood-brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study (English)

1 reference

Europe PubMed Central

16 October 2017

focused ultrasound

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blood–brain barrier

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based on heuristic

inferred from title

feasibility study

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

cancer immunotherapy

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based on heuristic

inferred from title

4

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Europe PubMed Central

16 October 2017

6

object named as

Hao-Li Liu

1 reference

Europe PubMed Central

16 October 2017

author name string

Pin-Yuan Chen

1

1 reference

Europe PubMed Central

16 October 2017

Han-Yi Hsieh

2

1 reference

Europe PubMed Central

16 October 2017

Chiung-Yin Huang

3

1 reference

Europe PubMed Central

16 October 2017

Kuo-Chen Wei

5

1 reference

Europe PubMed Central

16 October 2017

publication date

17 March 2015

1 reference

Europe PubMed Central

16 October 2017

Journal of Translational Medicine

1 reference

Europe PubMed Central

16 October 2017

13

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Europe PubMed Central

16 October 2017

93

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Europe PubMed Central

16 October 2017

copyright license

Creative Commons Attribution 4.0 International

17 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s12967-015-0451-y

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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

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A reversed CD4/CD8 ratio of tumor-infiltrating lymphocytes and a high percentage of CD4(+)FOXP3(+) regulatory T cells are significantly associated with clinical outcome in squamous cell carcinoma of the cervix

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Renal ultrafiltration changes induced by focused US.

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Angiostatin anti-angiogenesis requires IL-12: the innate immune system as a key target

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Ultrasound microbubble contrast agents: fundamentals and application to gene and drug delivery.

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Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

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Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications

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Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma.

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Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits

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IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk

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A dose-escalation and pharmacokinetic study of subcutaneously administered recombinant human interleukin 12 and its biological effects in Japanese patients with advanced malignancies

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Chemotherapy for high-grade gliomas

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Antitumor activity of interleukin 12 against interleukin 2-transduced mouse glioma cells.

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Systemic interleukin 12 displays anti-tumour activity in the mouse central nervous system

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20 June 2018

Antitumor activity of interleukin 12 in preclinical models

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20 June 2018

Adjuvant and neoadjuvant treatment for primary brain tumors in adults

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Antitumor and antimetastatic activity of interleukin 12 against murine tumors

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20 June 2018

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

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20 June 2018

Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the rodent: the factor of the blood-brain barrier

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20 June 2018

Therapeutic efficacy of multiagent chemotherapy with drug delivery enhancement by blood-brain barrier modification in glioblastoma.

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Growth of human lung tumor in the brain of the nude rat as a model to evaluate antitumor agent delivery across the blood-brain barrier.

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The fallacy of the localized supratentorial malignant glioma

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20 June 2018

Successful treatment of a malignant rat glioma with cytotoxic T lymphocytes

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20 June 2018

Improved long term survival after intracavitary interleukin-2 and lymphokine-activated killer cells for adults with recurrent malignant glioma.

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28 July 2018

Intratumoral LAK cell and interleukin-2 therapy of human gliomas.

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28 July 2018

Model selection in magnetic resonance imaging measurements of vascular permeability: Gadomer in a 9L model of rat cerebral tumor.

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21 January 2018

Paracrine delivery of IL-12 against intracranial 9L gliosarcoma in rats.

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In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma

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High-intensity focused ultrasound selectively disrupts the blood-brain barrier in vivo.

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Tumor growth reduction and DNA transfer by cavitation-enhanced high-intensity focused ultrasound in vivo.

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26 November 2018

Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma

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26 November 2018

Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene--a phase I/II clinical protocol.

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Identifiers

10.1186/S12967-015-0451-Y

1 reference

Europe PubMed Central

16 October 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12967-015-0451-y

1 reference

Europe PubMed Central

16 October 2017

1 reference

Europe PubMed Central

16 October 2017

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