Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism (Q30424658)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22472441%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism (English)

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27 January 2020

5

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27 January 2020

author name string

Erik S Welf

1

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27 January 2020

Shoeb Ahmed

2

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27 January 2020

Heath E Johnson

3

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27 January 2020

Adam T Melvin

4

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27 January 2020

language of work or name

English

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publication date

1 April 2012

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27 January 2020

published in

Journal of Cell Biology

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27 January 2020

volume

197

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27 January 2020

issue

1

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27 January 2020

page(s)

105-114

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In chemotaxing fibroblasts, both high-fidelity and weakly biased cell movements track the localization of PI3K signaling.

27 January 2020

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis

20 June 2018

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Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion

20 June 2018

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Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts

20 June 2018

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Integrins in cell migration--the actin connection

20 June 2018

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Quantification of local morphodynamics and local GTPase activity by edge evolution tracking

20 June 2018

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Visualizing and quantifying adhesive signals

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways.

20 June 2018

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Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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The locomotion of fibroblasts in culture I. Movements of the leading edge

20 June 2018

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20 June 2018

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Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions.

20 June 2018

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PI3-kinase signaling contributes to orientation in shallow gradients and enhances speed in steep chemoattractant gradients.

21 January 2018

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Analysis of cell movement by simultaneous quantification of local membrane displacement and fluorescent intensities using Quimp2.

21 January 2018

1 reference

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Coupling the dynamics of two actin networks--new views on the mechanics of cell protrusion.

21 January 2018

1 reference

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Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile Cells

21 January 2018

1 reference

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Chemotaxis in the Absence of PIP3 Gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201108152

21 January 2018

Identifiers

DOI

10.1083/JCB.201108152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22472441%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22472441%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22472441%20AND%20SRC:MED&resulttype=core&format=json