WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase (Q28244854)

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10 January 2020

title

WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase (English)

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10 January 2020

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4

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10 January 2020

author name string

Khalid Sossey-Alaoui

series ordinal

1

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10 January 2020

Xiurong Li

series ordinal

2

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10 January 2020

Tamara A Ranalli

series ordinal

3

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10 January 2020

language of work or name

English

0 references

publication date

11 April 2005

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Journal of Biological Chemistry

10 January 2020

published in

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10 January 2020

volume

280

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10 January 2020

issue

23

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10 January 2020

page(s)

21748-21755

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Actin-based cell motility and cell locomotion

10 January 2020

cites work

1 reference

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Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex

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Regulation of cortical actin networks in cell migration.

21 January 2018

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Genomic organization and expression profile of the human and mouse WAVE gene family

21 January 2018

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The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

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Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

21 January 2018

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Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

21 January 2018

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Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

21 January 2018

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IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

21 January 2018

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Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

21 January 2018

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Integration of signals to the Arp2/3 complex

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Purification and architecture of the ubiquitous Wave complex

21 January 2018

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Abi1 is essential for the formation and activation of a WAVE2 signalling complex

21 January 2018

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WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

21 January 2018

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WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility

21 January 2018

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A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

21 January 2018

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WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

21 January 2018

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Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

21 January 2018

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Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein

21 January 2018

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WAVE3, an actin-polymerization gene, is truncated and inactivated as a result of a constitutional t(1;13)(q21;q12) chromosome translocation in a patient with ganglioneuroblastoma

21 January 2018

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Biology of platelet-derived growth factors in development

21 January 2018

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Differential Roles of WAVE1 and WAVE2 in Dorsal and Peripheral Ruffle Formation for Fibroblast Cell Migration

21 January 2018

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PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

21 January 2018

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N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor

21 January 2018

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WAVE2 is required for directed cell migration and cardiovascular development

21 January 2018

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Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex

21 January 2018

1 reference

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Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation

21 January 2018

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Differential localization of WAVE isoforms in filopodia and lamellipodia of the neuronal growth cone

21 January 2018

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PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis

21 January 2018

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Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass

21 January 2018

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Cell migration: a physically integrated molecular process

21 January 2018

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The lamellipodium: where motility begins

21 January 2018

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Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

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The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

21 January 2018

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Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels

21 January 2018

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Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton

21 January 2018

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Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling

21 January 2018

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Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

21 January 2018

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SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

21 January 2018

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

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Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

21 January 2018

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Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M500503200

2 references

Consolidated OpenCitations Corpus – April 2017

1687189

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10 January 2020

1687189

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1687189