Modified heat-stable toxins (hSTa) of enterotoxigenic Escherichia coli lose toxicity but display antigenicity after being genetically fused to heat-labile toxoid LT(R192G). (Q30429806)

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English	Modified heat-stable toxins (hSTa) of enterotoxigenic Escherichia coli lose toxicity but display antigenicity after being genetically fused to heat-labile toxoid LT(R192G).	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

6 September 2017

Modified heat-stable toxins (hSTa) of enterotoxigenic Escherichia coli lose toxicity but display antigenicity after being genetically fused to heat-labile toxoid LT(R192G). (English)

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

enterotoxigenic Escherichia coli

1 reference

based on heuristic

inferred from title

Escherichia coli

1 reference

based on heuristic

inferred from title

4

object named as

James P Nataro

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Chengxian Zhang

2

object named as

Chengxian Zhang

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author name string

Mei Liu

1

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Kristy Mateo

3

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Donald C Robertson

5

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

Weiping Zhang

6

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

publication date

15 September 2011

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

1146-1162

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

copyright license

Creative Commons Attribution 4.0 International

15 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Escherichia coli K88ac fimbriae expressing heat-labile and heat-stable (STa) toxin epitopes elicit antibodies that neutralize cholera toxin and STa toxin and inhibit adherence of K88ac fimbrial E. coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Genetic fusions of heat-labile toxoid (LT) and heat-stable toxin b (STb) of porcine enterotoxigenic Escherichia coli elicit protective anti-LT and anti-STb antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Global, regional, and national causes of child mortality in 2008: a systematic analysis

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20 June 2018

Heat-stable enterotoxin of enterotoxigenic Escherichia coli as a vaccine target

1 reference

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20 June 2018

Diarrhoea: why children are still dying and what can be done

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20 June 2018

Escherichia coli constructs expressing human or porcine enterotoxins induce identical diarrheal diseases in a piglet infection model

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20 June 2018

Sentinel surveillance for travellers' diarrhoea in primary care

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20 June 2018

Protection of mice against rotavirus challenge following intradermal DNA immunization by Biojector needle-free injection

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20 June 2018

Association of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G).

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20 June 2018

Analysis of strategies to successfully vaccinate infants in developing countries against enterotoxigenic E. coli (ETEC) disease

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20 June 2018

Significance of heat-stable and heat-labile enterotoxins in porcine colibacillosis in an additive model for pathogenicity studies

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20 June 2018

Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

A review of vaccine research and development: human enteric infections

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries

1 reference

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20 June 2018

Vaccines for enterotoxigenic Escherichia coli: current status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Relative importance of heat-labile enterotoxin in the causation of severe diarrheal disease in the gnotobiotic piglet model by a strain of enterotoxigenic Escherichia coli that produces multiple enterotoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Structural features of Escherichia coli heat-stable enterotoxin that activates membrane-associated guanylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Effectiveness of a vaccine composed of heat-killed Candida albicans and a novel mucosal adjuvant, LT(R192G), against systemic candidiasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Effects of site-directed mutagenesis of Escherichia coli heat-labile enterotoxin on ADP-ribosyltransferase activity and interaction with ADP-ribosylation factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Diarrheagenic Escherichia coli

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Role of receptor binding in toxicity, immunogenicity, and adjuvanticity of Escherichia coli heat-labile enterotoxin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Occurrence, distribution, and associations of O and H serogroups, colonization factor antigens, and toxins of enterotoxigenic Escherichia coli

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Vaccines for preventing enterotoxigenic Escherichia coli infections in farm animals

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Immunological properties of Escherichia coli heat-stable enterotoxins: development of a radioimmunoassay specific for heat-stable enterotoxins with suckling mouse activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

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Observations on the pathogenic properties of the K88, Hly and Ent plasmids of Escherichia coli with particular reference to porcine diarrhoea

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

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Substitutions of cysteine residues of Escherichia coli heat-stable enterotoxin by oligonucleotide-directed mutagenesis

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Immunoactive chimeric ST-LT enterotoxins of Escherichia coli generated by in vitro gene fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

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Epidemiology of travelers' diarrhea and relative importance of various pathogens.

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Construction of a nontoxic fusion peptide for immunization against Escherichia coli strains that produce heat-labile and heat-stable enterotoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202872

20 June 2018

Molecular structure of the toxin domain of heat-stable enterotoxin produced by a pathogenic strain of Escherichia coli. A putative binding site for a binding protein on rat intestinal epithelial cell membranes

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Colonization factor antigens of enterotoxigenic Escherichia coli in animals

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Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli

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Mechanisms in the pathogenesis of diarrhea: a review

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LT(R192G), a non-toxic mutant of the heat-labile enterotoxin of Escherichia coli, elicits enhanced humoral and cellular immune responses associated with protection against lethal oral challenge with Salmonella spp.

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS3091146

21 January 2018

Intrarectal immunization of mice with VP6 and either LT(R192G) or CTA1-DD as adjuvant protects against fecal rotavirus shedding after EDIM challenge

1 reference

https://api.crossref.org/works/10.3390%2FTOXINS3091146

21 January 2018

Genetic fusions of heat-labile (LT) and heat-stable (ST) toxoids of porcine enterotoxigenic Escherichia coli elicit neutralizing anti-LT and anti-STa antibodies

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https://api.crossref.org/works/10.3390%2FTOXINS3091146

21 January 2018

A comparative molecular field analysis (COMFA) of the structural determinants of heat-stable enterotoxins mediating activation of guanylyl cyclase C.

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https://api.crossref.org/works/10.3390%2FTOXINS3091146

21 January 2018

Development of a competitive enzyme-linked immunosorbent assay (ELISA) for Escherichia coli heat-stable enterotoxin (STa)

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https://pubmed.ncbi.nlm.nih.gov/22069760

12 December 2020

based on heuristic

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A long-acting heat-stable enterotoxin analog of enterotoxigenic Escherichia coli with a single D-amino acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22069760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.3390/TOXINS3091146

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 September 2017

ResearchGate publication ID

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