Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65. (Q30439607)

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English	Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.	scientific article

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65. (English)

1 reference

Europe PubMed Central

15 August 2017

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Kaiser M Bijli

1

1 reference

Europe PubMed Central

15 August 2017

Fabeha Fazal

2

1 reference

Europe PubMed Central

15 August 2017

Mohd Minhajuddin

3

1 reference

Europe PubMed Central

15 August 2017

Arshad Rahman

4

1 reference

Europe PubMed Central

15 August 2017

language of work or name

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publication date

24 March 2008

1 reference

Europe PubMed Central

15 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

15 August 2017

283

1 reference

Europe PubMed Central

15 August 2017

21

1 reference

Europe PubMed Central

15 August 2017

14674-14684

1 reference

Europe PubMed Central

15 August 2017

Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.

1 reference

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c-Src mediates thrombin-induced NF-kappaB activation and IL-8/CXCL8 expression in lung epithelial cells

1 reference

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Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells

1 reference

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Src and Syk kinases: key regulators of phagocytic cell activation.

1 reference

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The non-receptor tyrosine kinase Syk regulates lamellipodium formation and site-directed migration of human leukocytes.

1 reference

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Functional role of c-Src in IL-1-induced NF-kappa B activation: c-Src is a component of the IKK complex

1 reference

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Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells

1 reference

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RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65.

1 reference

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Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells

1 reference

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Nuclear factor-kappaB: the enemy within

1 reference

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Signaling to NF-kappaB

1 reference

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1 reference

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Activation of Syk protein tyrosine kinase in response to osmotic stress requires interaction with p21-activated protein kinase Pak2/gamma-PAK.

1 reference

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Thrombin and Phenotypic Modulation of the Endothelium

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Tyrosine Kinase p56 Regulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of IκBα following Hypoxia/Reoxygenation

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Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease

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Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

1 reference

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Regulation of airway epithelial cell NF-kappa B-dependent gene expression by protein kinase C delta

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IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide

1 reference

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

1 reference

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Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation

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Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase.

1 reference

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Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

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IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

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Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism.

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Syk activation is required for spreading and H2O2 release in adherent human neutrophils

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Thrombin specificity

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Human vascular endothelial cells in culture. Growth and DNA synthesis

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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1 reference

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The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B

1 reference

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Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis

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Syk is required for integrin signaling in neutrophils

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Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Aerosolized Syk antisense suppresses Syk expression, mediator release from macrophages, and pulmonary inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

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inferred from PubMed ID database lookup

CD11/CD18-dependent and -independent neutrophil emigration in the lungs: how do neutrophils know which route to take?

1 reference

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based on heuristic

inferred from PubMed ID database lookup

A critical role for Syk in endothelial cell proliferation and migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin, TNF-alpha, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18362147

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M802094200

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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