Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled. (Q30440422)

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21 January 2020

title

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled (English)

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21 January 2020

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3

Roderick A Capaldi

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21 January 2020

author name string

Paula M Keeney

series ordinal

1

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21 January 2020

Jing Xie

series ordinal

2

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21 January 2020

James P Bennett

series ordinal

4

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21 January 2020

language of work or name

English

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publication date

1 May 2006

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21 January 2020

published in

Journal of Neuroscience

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21 January 2020

volume

26

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21 January 2020

issue

19

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21 January 2020

page(s)

5256-5264

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Human complex I defects can be resolved by monoclonal antibody analysis into distinct subunit assembly patterns

21 January 2020

cites work

1 reference

12 December 2020

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

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12 December 2020

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

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12 December 2020

The rotenone model of Parkinson's disease: genes, environment and mitochondria

1 reference

12 December 2020

Identification and characterization of a common set of complex I assembly intermediates in mitochondria from patients with complex I deficiency

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12 December 2020

Characterization of superoxide-producing sites in isolated brain mitochondria

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12 December 2020

Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies.

1 reference

12 December 2020

The mitochondrial production of reactive oxygen species in relation to aging and pathology

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12 December 2020

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

1 reference

12 December 2020

Human mitochondrial complex I assembles through the combination of evolutionary conserved modules: a framework to interpret complex I deficiencies.

1 reference

12 December 2020

MPTP as a mitochondrial neurotoxic model of Parkinson's disease

1 reference

12 December 2020

Mitochondrial ND5 mutations in idiopathic Parkinson's disease

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12 December 2020

Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids

1 reference

12 December 2020

Mitochondrial dysfunction and possible treatments in Parkinson's disease--a review

1 reference

12 December 2020

Brain-derived growth factor and glial cell line-derived growth factor use distinct intracellular signaling pathways to protect PD cybrids from H2O2-induced neuronal death

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12 December 2020

Superoxide generation from mitochondrial NADH dehydrogenase induces self-inactivation with specific protein radical formation

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12 December 2020

Human mitochondrial complex I assembly is mediated by NDUFAF1.

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12 December 2020

1 reference

12 December 2020

Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication

1 reference

12 December 2020

Isocitrate Dehydrogenase and Malate Dehydrogenase in Synaptic and Non-Synaptic Rat Brain Mitochondria: A Comparison of their Kinetic Constants

1 reference

12 December 2020

Origin and functional consequences of the complex I defect in Parkinson's disease

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12 December 2020

Mitochondrial dysfunction in idiopathic Parkinson disease

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12 December 2020

Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease

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12 December 2020

10.1523/JNEUROSCI.0984-06.2006

Identifiers

DOI

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