Vinculin controls focal adhesion formation by direct interactions with talin and actin. (Q30441610)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056416%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Vinculin controls focal adhesion formation by direct interactions with talin and actin (English)

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29 December 2019

6

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29 December 2019

3

Charles Streuli

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29 December 2019

author name string

Jonathan D Humphries

1

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29 December 2019

Pengbo Wang

2

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29 December 2019

Benny Geiger

4

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29 December 2019

Martin J Humphries

5

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29 December 2019

language of work or name

English

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publication date

1 December 2007

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29 December 2019

number of pages

15

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inferred from page(s)

published in

Journal of Cell Biology

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29 December 2019

volume

179

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issue

5

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29 December 2019

page(s)

1043-1057

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describes a project that uses

29 December 2019

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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Differential transmission of actin motion within focal adhesions

20 June 2018

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Shigella applies molecular mimicry to subvert vinculin and invade host cells

20 June 2018

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Coincidence of actin filaments and talin is required to activate vinculin

20 June 2018

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20 June 2018

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Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration

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20 June 2018

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Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

20 June 2018

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A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

20 June 2018

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Two distinct actin networks drive the protrusion of migrating cells

20 June 2018

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20 June 2018

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Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

20 June 2018

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Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

20 June 2018

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Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Vinculin knockout results in heart and brain defects during embryonic development.

20 June 2018

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Characterization of two F-actin-binding and oligomerization sites in the cell-contact protein vinculin

20 June 2018

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20 June 2018

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20 June 2018

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Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

20 June 2018

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Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin

20 June 2018

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Characterization of an F-actin-binding domain in the cytoskeletal protein vinculin

20 June 2018

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20 June 2018

1 reference

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Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

20 June 2018

1 reference

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Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion

20 June 2018

1 reference

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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

20 June 2018

1 reference

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Paxillin: a new vinculin-binding protein present in focal adhesions

20 June 2018

1 reference

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A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions.

20 June 2018

1 reference

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Three-dimensional structure of vinculin bound to actin filaments

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099183

The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099183

Characterization of an Actin-binding Site within the Talin FERM Domain

26 November 2018

1 reference

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Structural basis for vinculin activation at sites of cell adhesion.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099183

Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation.

26 November 2018

1 reference

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Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

26 November 2018

1 reference

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The interaction of the cell-contact proteins VASP and vinculin is regulated by phosphatidylinositol-4,5-bisphosphate.

26 November 2018

1 reference

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Focal adhesion formation by F9 embryonal carcinoma cells after vinculin gene disruption.

26 November 2018

1 reference

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Role of vinculin in regulating focal adhesion turnover

26 November 2018

1 reference

12 December 2020

The ultrastructure of chicken gizzard vinculin as visualized by high-resolution electron microscopy

1 reference

12 December 2020

A conformational switch in vinculin drives formation and dynamics of a talin-vinculin complex at focal adhesions

1 reference

12 December 2020

Molecular shape of vinculin in aqueous solution

1 reference

12 December 2020

Monoclonal antibody 9EG7 defines a novel beta 1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200703036

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056416%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056416%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference