Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity (Q30442556)

14 August 2017

Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity (English)

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14 August 2017

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5

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21 June 2017

Anil Kumar

1

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14 August 2017

Thurl E Harris

2

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14 August 2017

Susanna R Keller

3

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14 August 2017

Kin M Choi

4

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14 August 2017

John C Lawrence

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14 August 2017

language of work or name

English

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publication date

29 October 2007

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Molecular and Cellular Biology

14 August 2017

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14 August 2017

28

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14 August 2017

1

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14 August 2017

61-70

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describes a project that uses

14 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2223287/fullTextXML

inferred from PubMed Central ID database lookup

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

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Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

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How many signals impinge on GLUT4 activation by insulin?

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Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

20 June 2018

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PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

20 June 2018

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

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A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

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20 June 2018

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20 June 2018

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Control of glycogen synthesis is shared between glucose transport and glycogen synthase in skeletal muscle fibers

20 June 2018

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20 June 2018

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20 June 2018

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

20 June 2018

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20 June 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

20 June 2018

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Mechanism of activation of protein kinase B by insulin and IGF-1

20 June 2018

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

20 June 2018

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Increased glycogen accumulation in transgenic mice overexpressing glycogen synthase in skeletal muscle

20 June 2018

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20 June 2018

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Three genes for protein phosphatase 1 map to different human chromosomes: sequence, expression and gene localisation of protein serine/threonine phosphatase 1 beta (PPP1CB).

20 June 2018

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Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg-dependent protein phosphatase

20 June 2018

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Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase

20 June 2018

1 reference

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A comparison of three methods of glycogen measurement in tissues.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

Glucose transport and glucose transporters in muscle and their metabolic regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

Pathogenesis of NIDDM. A balanced overview

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

Glucose metabolism in mice lacking muscle glycogen synthase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223287

An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts

26 November 2018

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12 December 2020

A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose

1 reference

12 December 2020

Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo

1 reference

12 December 2020

Control of glycogen synthase by insulin and isoproterenol in rat adipocytes. Changes in the distribution of phosphate in the synthase subunit in response to insulin and beta-adrenergic receptor activation

1 reference

12 December 2020

Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1 reference

12 December 2020

Phosphorylation of the glucose transporter in rat adipocytes. Identification of the intracellular domain at the carboxyl terminus as a target for phosphorylation in intact-cells and in vitro

1 reference

12 December 2020

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

1 reference

12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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12 December 2020

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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12 December 2020

Identifiers

DOI

10.1128/MCB.01405-07

1 reference

14 August 2017

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14 August 2017

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