Engulfment of apoptotic cells: signals for a good meal (Q30445079)

21 June 2017

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title

Engulfment of apoptotic cells: signals for a good meal (English)

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21 June 2017

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Ulrike Lorenz

2

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Kodi Ravichandran

series ordinal

1

object named as

Kodi S Ravichandran

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21 June 2017

1 December 2007

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Nature Reviews Immunology

21 June 2017

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21 June 2017

7

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21 June 2017

964-974

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21 June 2017

12

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Apoptotic cell removal in development and tissue homeostasis

21 June 2017

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Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization

31 March 2020

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The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically?

31 March 2020

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Mechanisms of phagocytosis in macrophages

31 March 2020

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Corpse clearance defines the meaning of cell death

31 March 2020

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Clearance of apoptotic cells: getting rid of the corpses.

31 March 2020

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31 March 2020

Dampening inflammation

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Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease

31 March 2020

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Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

31 March 2020

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Phagocytosis promotes programmed cell death in C. elegans

31 March 2020

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"Recruitment signals" from apoptotic cells: invitation to a quiet meal

31 March 2020

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Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

31 March 2020

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Plasma ceramide and lysophosphatidylcholine inversely correlate with mortality in sepsis patients

31 March 2020

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UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

31 March 2020

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Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages.

31 March 2020

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Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2-26)

31 March 2020

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31 March 2020

Apoptotic cell removal

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A blast from the past: clearance of apoptotic cells regulates immune responses.

31 March 2020

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The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

31 March 2020

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Human CD14 mediates recognition and phagocytosis of apoptotic cells

31 March 2020

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CD14 is a component of multiple recognition systems used by macrophages to phagocytose apoptotic lymphocytes

31 March 2020

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Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cells

31 March 2020

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Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

31 March 2020

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Macrophage-restricted molecules: role in differentiation and activation

31 March 2020

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Roles of ICAM-3 and CD14 in the recognition and phagocytosis of apoptotic cells by macrophages.

31 March 2020

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Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte

31 March 2020

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C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

31 March 2020

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Multiple systems for recognition of apoptotic lymphocytes by macrophages.

31 March 2020

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Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells

31 March 2020

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Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases

31 March 2020

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Identification of a factor that links apoptotic cells to phagocytes

31 March 2020

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Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

31 March 2020

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Annexin I Is an Endogenous Ligand that Mediates Apoptotic Cell Engulfment

31 March 2020

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Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells

31 March 2020

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A receptor for phosphatidylserine-specific clearance of apoptotic cells

31 March 2020

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

31 March 2020

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Natural adjuvants: endogenous activators of dendritic cells

31 March 2020

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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

31 March 2020

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Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

31 March 2020

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A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis

31 March 2020

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Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine.

31 March 2020

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The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal

31 March 2020

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The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity

31 March 2020

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The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells

31 March 2020

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Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor

31 March 2020

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Phosphatidylserine receptor is required for clearance of apoptotic cells

31 March 2020

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Recognition ligands on apoptotic cells: a perspective

31 March 2020

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BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

31 March 2020

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Phosphatidylserine recognition by phagocytes: a view to a kill

31 March 2020

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Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes.

31 March 2020

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31 March 2020

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Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

31 March 2020

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How the worm removes corpses: the nematode C. elegans as a model system to study engulfment.

31 March 2020

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CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

31 March 2020

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The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

31 March 2020

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C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

31 March 2020

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C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

31 March 2020

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The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway

31 March 2020

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CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans

31 March 2020

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C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells

31 March 2020

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Rho family proteins: coordinating cell responses

31 March 2020

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Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins

31 March 2020

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Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages

31 March 2020

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Engulfment of Apoptotic Cells Is Negatively Regulated by Rho-mediated Signaling

31 March 2020

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Rocks: multifunctional kinases in cell behaviour

31 March 2020

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Rho-kinase and myosin-II control phagocytic cup formation during CR, but not FcgammaR, phagocytosis

31 March 2020

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Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells

31 March 2020

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alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells

31 March 2020

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Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

31 March 2020

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Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells.

31 March 2020

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Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells

31 March 2020

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Dock180-ELMO cooperation in Rac activation

31 March 2020

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CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

31 March 2020

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Evidence for a conserved role for CRKII and Rac in engulfment of apoptotic cells

31 March 2020

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DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

31 March 2020

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Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

31 March 2020

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Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

31 March 2020

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Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO

31 March 2020

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Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

31 March 2020

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Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins

31 March 2020

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CZH proteins: a new family of Rho-GEFs

31 March 2020

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A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

31 March 2020

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PH domain of ELMO functions in trans to regulate Rac activation via Dock180

31 March 2020

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RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

31 March 2020

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Characterization of a novel interaction between ELMO1 and ERM proteins

31 March 2020

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Requirement for a Drosophila E3-ubiquitin ligase in phagocytosis of apoptotic cells.

31 March 2020

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Elmo1 inhibits ubiquitylation of Dock180

31 March 2020

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Phagocytosis and clearance of apoptotic cells is mediated by MER.

31 March 2020

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Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

31 March 2020

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Apoptosis and autoimmunity: when apoptotic cells break their silence.

31 March 2020

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Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice

31 March 2020

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Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo

31 March 2020

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Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.

31 March 2020

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Requirements for apoptotic cell contact in regulation of macrophage responses

31 March 2020

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Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype

31 March 2020

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Immunosuppressive effects of apoptotic cells

31 March 2020

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Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells

31 March 2020

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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

31 March 2020

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Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition

31 March 2020

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TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells

31 March 2020

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Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia

31 March 2020

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Mechanisms of disease: macrophage-derived foam cells emerging as therapeutic targets in atherosclerosis

31 March 2020

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

31 March 2020

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Metabolism and functions of phosphatidylserine

31 March 2020

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A subfamily of P-type ATPases with aminophospholipid transporting activity

31 March 2020

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Aminophospholipid translocase TAT-1 promotes phosphatidylserine exposure during C. elegans apoptosis.

31 March 2020

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Phospholipid scramblases: an overview

31 March 2020

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Two alternative mechanisms that regulate the presentation of apoptotic cell engulfment signal in Caenorhabditis elegans

31 March 2020

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C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1.

31 March 2020

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Transbilayer phospholipid movement and the clearance of apoptotic cells

31 March 2020

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Identification of Tim4 as a phosphatidylserine receptor

31 March 2020

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Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI2214

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21 June 2017

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PubMed ID

18037898